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A common medicine used to relieve mild to moderate pain and reduce fever. Acetaminophen (N-acetyl-p-aminophenol), or paracetamol, is a white crystalline compound with the molecular formula C8H9NO2 (Fig. 1). It is a member of the aniline family of…

A disease of the nervous system characterized by a progressive dementia that leads to profound impairment in cognition and behavior. Dementia occurs in a number of brain diseases where the impairment in cognitive abilities represents a decline from…

A member of a group of organic compounds that can be considered as derived from ammonia by replacement of one or more hydrogens by organic functional groups. Generally amines are bases of widely varying strengths, but a few that are acidic are…

An analytical technique for determining the composition of a sample in terms of the chemical elements present and their quantities or concentrations. Unlike other methods of elemental analysis, however, the sample is decomposed into its constituent…

A neurodevelopmental condition that impairs the way that a person relates to and communicates with other people. Persons with autism have difficulties with social communication and interaction. They also can have unusual behaviors, such as…

A poisonous colorless, odorless, tasteless gas (CO), resulting from the incomplete combustion of carbon-containing materials. Carbon monoxide (Fig. 1) is an indoor hazard causing hundreds of deaths annually, and it is one of the six major air…

The attractive force that holds atoms or ions together. Chemical bonds are very strong. To break one bond in each molecule in a mole of material typically requires an energy of many tens of kilocalories.It is convenient to classify chemical bonding…

A chemical element, Cl, atomic number 17 and atomic weight 35.453. Chlorine exists as a greenish-yellow gas at ordinary temperatures and pressures (see illustration). It is second in reactivity only to fluorine among the halogen elements, and hence…

A psychotherapy with roots in both cognitive science and behavioral science. Cognitive-behavioral therapy (CBT) is the most widely used evidence-based psychotherapeutic practice for a variety of mental health disorders, including anxiety, depression…

The use of pollen and spore evidence in legal cases. In its broader application, the field of forensic palynology also includes legal information derived from the analysis of a broad range of microscopic organisms that can be found in both fresh and…

In thermodynamics, the amount of useful work that can be extracted from a closed thermodynamic system. The Helmholtz free energy applies to a process that takes place at a constant temperature T (isothermal process). The Gibbs free energy applies to…

A biological organism whose genetic material has been manipulated artificially through genetic or genomic editing techniques. In contrast to the long history of artificial selection (domestication), in which humans selectively breed organisms to…

A salt or ester of lactic acid (CH3CHOHCOOH). In lactates, the acidic hydrogen of the carboxyl group has been replaced by a metal or an organic radical. Lactates are optically active, with a chiral center at carbon 2. The two optical isomers of a…

An analytical technique for identification of chemical structures, determination of mixtures, and quantitative elemental analysis by measuring the mass-to-charge (m/z) ratio of ions produced when a sample is ionized. Determination of organic and…

A device that is capable of converting chemical energy into electrical energy with the use of whole bacterial cells as the catalyst. Fuels that are produced biologically are known as biofuels. Biofuel cells convert chemical energy from organic…

A chemical element, Os, atomic number 76, atomic weight 190.2. Osmium is a hard white metal of rare natural occurrence, and is usually found in nature alloyed with other platinum metals. Metal Periodic table Platinum The periodic table of the…

A two-component reaction involving the loss of electrons (oxidation) by one chemical species and the gain of electrons (reduction) by another; also known as a redox reaction. Both oxidation and reduction occur simultaneously and in equivalent…

The study of chemical changes resulting from the absorption of high-energy ionizing radiation. Such radiation includes alpha particles, electrons, gamma rays, fission fragments, protons, deuterons, helium nuclei, and heavier charged projectiles.…

One of the elements of atomic numbers 21–31, 39–49, and 71–81. The symbols of these elements, along with their atomic numbers and valence-shell electronic configurations, are given in Fig. 1. The elements are arranged in the order in which they…

A chemical obtained from wood. Woody plants comprise the greatest part of the organic materials produced by photosynthesis on a renewable basis. Replacement of fossil hydrocarbons, from which most organic chemicals are derived, is possible in many…

The scattering of x-rays by matter with accompanying variation in intensity for specific directions (or wavelengths) due to interference effects. X-ray diffraction is a powerful and readily available method for determining atomic arrangements in…

A plant, Musa textilis, of the banana family that is valuable for its hard fiber (also known as Manila hemp). Abaca (Musa textilis) is a flowering plant native to the Philippines and Borneo. Taxonomically, it is assigned to the order Zingiberales.…

A major plant hormone that plays an important role in plant growth and development. Abscisic acid (ABA), with a chemical formula of C15H20O4 (Fig. 1), is one of the most significant hormones found in plants. It is responsible for regulating various…

Habituation to a specific practice, such as drinking alcoholic beverages or using drugs (for example, heroin, cocaine, or amphetamines), and disorders characterized by the chronic use of a drug, alcohol, or similar substance. Addiction and addictive…

Any disorder of recognition. Agnosia is a rare neurological condition in which an individual fails to recognize and identify persons or objects (see illustration). Typically, agnosia is the result of damage to specific areas of the brain.…

The repeated and/or excessive use of alcohol (ethanol) that continues despite negative physical, psychiatric, or social consequences. Alcoholism is characterized by consuming alcohol more often, in larger amounts, or over longer periods than…

A useful carbon-carbon bond-forming reaction in which aldehyde and alcohol functional groups are observed during the reaction. The aldol reaction was first reported by Aleksandr Porfiryevich Borodin, who observed the reaction using pentanal and…

An informal assemblage of predominantly aquatic eukaryotes that carry out oxygen-evolving photosynthesis, but lack specialized water-conducting and food-conducting tissues. Algae (Fig. 1) are eukaryotic organisms (having an organized nucleus).…

A significant, yet relatively selective loss of memory. Amnesia is a type of memory loss, often resulting from brain disease or injury (see illustration). The inability to remember can be temporary or permanent. In general, amnesia can be…

The use of live nonhuman animals for scientific research and experimentation. Animal testing has been a cornerstone of biomedical research, having contributed greatly to the understanding of human biology, to the unraveling of the complex underlying…

A disorder of language acquired as a result of brain disease. Aphasia is impairment in the use of spoken or written language caused by brain disorders (see illustration) that cannot be explained by paralysis or incoordination of the articulatory…

An impairment in the performance of voluntary actions despite intact motor power and coordination, sensation and perception, and comprehension. Apraxia is a neurological condition in which there is difficulty with skilled tasks or learned movements…

A chemical reaction or series of reactions leading to the predominant or exclusive formation of a single enantiomer, that is, one of an isomeric pair of chemical compounds whose molecules are nonsuperimposable mirror images. Enantiomers are said to…

A common psychiatric disorder (especially in children) characterized by attentional difficulties, impulsivity, and hyperactivity. Attention deficit hyperactivity disorder (ADHD) is a mental disorder marked by an individual's inability to pay…

Any of a class of plant growth substances (phytohormones or plant hormones) that have an essential role in coordination of many growth and developmental processes during the life cycle of plants, especially the ability to increase the rate of shoot…

A class of nonflagellate unicellular algae, commonly called diatoms, with boxlike silicified walls. Members of the algal class Bacillariophyceae are commonly termed diatoms (Fig. 1). Diatoms range in maximum dimension from 4 μm (0.00004 in.) to more…

Any of several leguminous plants, or their seeds, long utilized as food by humans or livestock. There are more than 40,000 varieties of beans, with only a small number of these being mass-produced for human or animal consumption. In particular,…

The drug as well as the plant known as deadly nightshade (Atropa belladonna). The belladonna plant (Atropa belladonna; see illustration) belongs to the nightshade family, Solanaceae, in the order Solanales. The plant is a coarse and poisonous…

An aromatic hydro­carbon, molecular formula C6H6, also know as benzol. Benzene is a clear, colorless, and flammable liquid which boils at 80.1°C and freezes at 5.5°C.Benzene (1) is an important chemical intermediate used to produce ethylbenzene…

Fungi that exhibit the natural phenomenon of bioluminescence (the ability of an organism to emit visible light). Bioluminescence is the emission of photons of visible light by living organisms via the chemical reaction of molecular oxygen (O2) with…

An integrated device consisting of a biological recognition element and a transducer capable of detecting the biological reaction and converting it into a signal that can be processed. Ideally, the sensor should be self-contained, so that it is not…

A major mental disorder in which there are lifelong episodes of both mania and depression; also known as manic-depressive illness. Bipolar disorder, also termed manic-depressive illness or manic depression, is characterized by sudden and often…

A mental health illness characterized by a compulsive or obsessive focus on a perceived flaw in appearance. Body dysmorphic disorder (often abbreviated BDD) is a psychiatric illness in which a person has a severe, excessive preoccupation with a…

A garden for the culture of plants collected chiefly for scientific, educational, and esthetic purposes. A botanical garden (see illustration) is an establishment in which various plants, including trees, are collected, cultivated, and grown for…

The branch of biological science that embraces the study of plants and plant life. Botany is the scientific study of plants (see illustration), encompassing investigations of plant anatomy, physiology, genetics, phylogeny, ecology, pathology, and…

A division that consists of small and relatively simple plants commonly known as mosses, peat mosses, granite mosses, liverworts, and hornworts. Members of the division Bryophyta are referred to as bryophytes (see illustration). These nonvascular…

The measurement of the quantity of heat transferred during chemical reactions, changes of state, mixing of substances, as well as other chemical and physical processes. The unit of energy in the International System of Units is the joule, symbolized…

A genus comprising yeasts that cause a variety of human diseases referred to as candidiasis. All Candida species are single-celled yeasts (fungal organisms) that are ovoid in shape and 3–5 μm in size, and they multiply by a process called budding.…

An order of flowering plants (angiosperms) including the mustard and caper families. The plant order Capparales contains various families of eurosid dicotyledons. Most notably, mustards, capers, and various ornamental plants (see illustration) are…

A member of a class of common pigments, typically of yellow, orange, or red hues, that serve in both light absorption and the protection against too much light in photosynthesis as well as in the vision process. Carotenoids comprise a class of…

A branch of physical chemistry that seeks to explain time-dependent phenomena, such as energy transfer and chemical reaction, in terms of the detailed motion of the nuclei and electrons that constitute the system. As such, chemical dynamics seeks…

A type of sweet or sour fruit of the Prunus genus, as well as the tree that bears the fruit. Cherry trees belong to the Prunus genus in the order Rosales, and the sweet and sour fruits of these trees are called cherries (Fig. 1). There are…

A white or colorless amorphous polysaccharide that forms a base for the hard outer integuments of crustaceans, insects, and other invertebrates. Chitin (see illustration) is an important nitrogenous polysaccharide that is found abundantly in nature.…

A large palm, Cocos nucifera, widely grown throughout the tropics and valuable for its fruit and fiber. The coconut (Cocos nucifera) belongs to the plant family Arecaceae. The name coconut can refer to the tree and its fruit. Usually found near the…

Any of various tropical trees belonging to the genus Cola. Members of the genus Cola (family Malvaceae, order Malvales), which are native to tropical Africa, are called cola trees (see illustration). In particular, two species, C. acuminata and C.…

Any living or fossil member of the plant division Pinophyta, consisting chiefly of woody trees or shrubs that produce cones and evergreen needles. Conifers are predominantly cone-bearing, evergreen trees and shrubs belonging to the order Pinales, as…

A fiber obtained from the cotton plant Gossypium. The cotton plant (genus Gossypium, order Malvales; Fig. 1) has been used by humans for more than 5000 years. The fiber (cotton) obtained from this plant is the most widely used natural fiber because…

A woody higher plant that regularly loses its leaves at the end of each growing season. Deciduous plants drop (shed) their leaves seasonally, most commonly during the fall (autumn). In general, the dropping of leaves occurs at the inception of an…

A syndrome characterized by a generalized decline in cognition that is severe enough to cause functional impairment in daily activities. Dementia is a term used to describe a collection of symptoms of severe cognitive decline. Individuals suffering…

A heterogeneous affective disorder involving a depressed mood and/or a loss of interest in daily activities. The most common form of affective disorder is depression (also termed clinical depression) [Fig. 1]. A major depressive episode is defined…

A cycloaddition reaction between a diene and a dienophile. The simplest Diels-Alder reaction (O. Diels and K. Alder, 1928) occurs between butadiene and ethylene and is often referred to as a [4+2] cycloaddition. The numbers, four and two in…

The transport of matter from one point to another by random molecular motions. Diffusion occurs in gases, liquids, and solids.Diffusion plays a key role in processes as diverse as permeation through membranes, evaporation of liquids, dyeing textile…

A system that delivers controlled amounts of a therapeutic agent over a prolonged period or in a desirable temporal fashion, thereby maintaining required plasma or tissue drug levels. Drug delivery systems are bioengineered mechanisms or devices…

Impairment of the ability to read. Developmental dyslexia, which is a learning disorder with a neurobiological basis, is characterized by unexpected difficulty in reading in children and adults who otherwise possess the intelligence and motivation…

The controlled induction of a grand mal seizure under anesthesia to treat individuals suffering from certain psychiatric illnesses. Electroconvulsive therapy (ECT; Fig. 1) was introduced as a treatment for psychiatric disorders by the Italian…

A major clade or natural group of plants, comprising the land plants. The members of the Embryobionta or Embryophyta are commonly termed embryobionts or embryophytes, and they constitute the land plants. Embryophytes form a well-marked clade (a…

A volatile, fragrant oil obtained from plants. Essential oils are distinguished from those known as fixed oils, which are mainly triglycerides of fatty acids. Essential oils have been obtained from thousands of plants (Fig. 1) and are designated and…

The simplest cyclic ether or epoxide, with the formula C2H4O. Ethylene oxide is also called epoxyethane and oxirane, and has the below structure. Ethylene oxide was discovered in 1859 by C. A. Wurtz. His preparation from ethylene chlorohydrin and…

A former order of rosid flowering plants, division Magnoliophyta (Angiospermae), in the class Magnoliopsida (dicotyledons). The order Euphorbiales consisted of the large family Euphorbiaceae (with about 7500 species) and 3 small satellite families…

An active and intentional act or practice of putting to death, in a relatively painless way, of persons suffering severely from medical conditions that are incurable, untreatable, or irreversible. Euthanasia is an act by a person, usually a…

A plant that retains its green foliage throughout the year. An evergreen plant, or simply evergreen, is a tree, shrub, or plant whose leaves are not shed in the winter and instead remain green year-round. In contrast, deciduous trees and plants…

The test of a hypothesis under controlled conditions. The experiment is one of the distinctive tools of the scientist. It enables the scientist to put questions to nature and receive answers. These answers lead to new problems whose solutions…

A method of separating the constituents of a mixture using preferential solubility of one or more components in a second phase. Commonly, this added phase is a liquid, while the mixture to be separated may be either solid or liquid. For example, the…

A method of quantitative multivariate analysis with the goal of representing the interrelationships among a set of continuously measured variables (usually represented by their intercorrelations) by a number of underlying, linearly independent…

A plant grown for its fibrous material, which is used for many commercial purposes and for home industry. Many plants are grown as fiber crops because of their content or yield of fibrous material (see illustration), which is used in the manufacture…

The segment of horticulture concerned with the commercial production, marketing, and sale of plants grown and used for decorative or display purposes. Floriculture is a branch of horticulture, that is, the art and science of growing plants,…

A hypersensitivity or altered reactivity caused by fungal allergens. More than 20% of the population in industrialized countries suffers from allergic disease, and diverse allergens (substances foreign to the body that cause allergy) associated with…

Qualitative identifications and quantitative determinations of substances essential for the evaluation of the air quality in the ambient air and in the industrial workplace.The terms air pollution and gas analysis are used here in the broad sense.…

A member of a family of diterpenoid carboxylic acids that are notable for being plant hormones. Gibberellins are diterpenoid carboxylic acids. Most of them possess ent-gibberellane or ent-20-norgibberellane carbon (C) skeletons. Gibberellins occur…

The common name for plants of the genus Vitis characterized by climbing stems and grown for the edible, pulpy berries. Grapes (genus Vitis) comprise one of the world's most significant and economically important crops. The common grapevine is…

An evergreen tree (Citrus paradisi) and its edible citrus fruit. Grapefruit (Citrus paradisi) is a subtropical evergreen tree belonging to the order Sapindales. It has a well-rounded top and is cultivated for its large and globose citrus fruit. The…

Any member of the family Poaceae (Gramineae) cultivated as forage and grain for consumption. Grasses are arguably the most useful of all the plants that cover the Earth. The cereal grass crops [wheat (Fig. 1), rice, corn (maize), rye, barley, oats,…

The discovery, development, and application of sustainable chemical reactions that create no waste or generate only benign wastes. The idea that toxic chemicals, once created, can be contained or prevented from entering the environment is…

A morphologically distinct cell that is found in the epidermis of terrestrial plant shoots and that functions in regulating stoma size. Guard cells are paired, crescent-shaped epidermal cells that regulate water loss and gas exchange in terrestrial…

An aliphatic or aromatic hydrocarbon in which one or more hydrogen atoms are substituted by halogen atoms. Alkyl halides Alkyl halides are compounds in which one hydrogen of an alkane has been replaced by halogen [fluorine (F), chlorine (Cl),…

A class of lower green plants called liverworts that belong to the division Bryophyta. The class Hepaticopsida, also called Marchantiopsida, comprises the liverworts, which are nonvascular land plants. Although there is a great diversity of external…

The collective techniques for supplying nutrients and water directly to the roots of plants, without soil or other media. Hydroponics is concerned with the cultivation and growing of plants without soil or other media. Hydroponic systems (Fig. 1)…

A tentative supposition with regard to an unknown state of affairs, the truth of which is thereupon subject to investigation by any available method, either by logical deduction of consequences which may be checked against what is known, or by…

A chemical element, Fe, atomic number 26, and atomic weight 55.845. Iron is a malleable, tough, silver-gray, magnetic metal. It melts at 1540°C, boils at 2800°C, and has a density of 7.86 g/cm3. The four stable, naturally occurring isotopes have…

An order of flowering plants composed of seven eumagnoliid families of tropical tree and shrub species. The plant order Laurales, with approximately 2500–2800 species, contains numerous trees and shrubs having ecological significance. Members of the…

Citrus limon, a small evergreen tree belonging to the order Sapindales that is cultivated for its fruit. In commercial terms, the lemon (Citrus limon; order Sapindales) is the most important of the acid citrus fruits (see illustration). It probably…

One of the largest orders of the rosid eudicotyledons. The order Malpighiales is an important flowering plant group with a worldwide distribution. Depending on the classification, it contains approximately 35 to 40 families, totaling about 16,000…

An order of flowering plants in the core eudicots. The plant order Malvales consists of 10 families and approximately 6000 species (see illustration). The circumscription of the order Malvales has been altered greatly as a result of deoxyribonucleic…

A solid or liquid (molten), opaque material with a lustrous surface and good electrical and thermal conductivities. Solid metal is usually crystalline and ductile and can be permanently deformed by shear on crystal planes (Fig. 1); permanent…

A type of protein that shuttles metal ions to specific sites within a cell. Metallochaperones are molecular facilitators that transport metal ions to target proteins (see illustration). The target sites for metal delivery include a number of…

The body of knowledge that concerns the fundamental nature, function, development, and use of formal models in science and technology. In its most general sense, a model is a proxy. A model is one entity used to represent some other entity for some…

The smallest unit of a compound, which consists of atoms bonded together in a unique arrangement. A diatomic molecule consists of two atoms linked together by chemical bonds. Examples include the oxygen and nitrogen of the air (O2 and N2,…

A macroscopic fungus with a fruiting body. It has been estimated that 1.5 million to 5 million species of fungi exist on Earth. Yet, only about 150,000 species have been described to date. Approximately 50,000 fungal species are considered…

A class of chemicals characterized by their common chemical structure and potentially fatal nervous system effects. Development and historical use Research into organophosphate insecticides led to the development of nerve agents in the 1930s. Nerve…

The process of turning free nitrogen gas (N2) into chemical compounds, usually ammonia (NH3), which can be used by growing plants as a source of nitrogen. Gaseous N2 makes up the majority of the atmosphere, but higher organisms cannot use it because…