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Healthy neuron (top) and neuron affected by Tay-Sachs disease (bottom). Defective hexosaminidase A enzyme activities in the case of Tay-Sachs disease allow lipid substrates to be stored in lysosomal compartments. This abnormal storage becomes toxic,…

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from article Tay-Sachs disease

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from article Tay-Sachs disease

Tay-Sachs disease results from mutations of a gene known as the HEX A gene, which encodes the α-subunit of the hexosaminidase A enzyme. When both partners are mutation carriers, each pregnancy has a 25% chance of being affected. (Copyright ©…

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from article Pseudomonas

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from article Retrovirus

Different morphological types of retroviruses. (a) Murine mammary tumor virus, a Betaretrovirus, shown with its off-center core surrounded by an envelope. (b) Feline leukemia virus, a Gammaretrovirus, shown with its centrally located core. (c)…

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from article Smallpox

A transmission electron micrograph of smallpox viruses using a negative stain technique. (Credit: Frederick A. Murphy/U.S. Centers for Disease Control and Prevention)

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from article Thyroid gland disorders

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from article Thyroid gland disorders

Follicular adenomas constitute most thyroid neoplasms. The bottom half of the photomicrograph has a follicular adenoma, with a rim of normal thyroid gland seen in the remainder of the image. The follicular adenoma has a thin capsule (arrow). In…

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from article Strychnos