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A newly identified coronavirus, provisionally termed 2019-nCoV (an acronym for 2019 novel coronavirus) and subsequently named "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2), emerged in central China in November 2019. The disease…

Two new studies offer insight into why infection with SARS-CoV-2—the coronavirus that causes COVID-19—often leads to loss of smell, as well as why some people experience debilitating symptoms months after infection—a condition known as long COVID.…

Among the non-human animals that can be infected with—and become sick from—humans who have the SARS-CoV-2 virus that causes COVID-19 are deer, mink, hyenas, pigs, ferrets, dogs, cats, and primates such as rhesus macaque monkeys, baboons, and…

Bats are members of the order Chiroptera, which is the second-largest order of living mammals. The geographic distribution of these flying mammals is tremendous as well, ranging from the limit of trees in the Northern Hemisphere to the southern tips…

Genealogists and anthropologists have long disputed the provenance of domestic dogs (Canis lupus familiaris). Although genetic analyses and fossil evidence indicate that the domestic dog descended from the gray wolf (Canis lupus), the exact location…

A serious outbreak of equine herpesvirus type 1 (EHV-1), an infectious viral disease, is currently spreading among horse populations in Europe. This outbreak was first detected in Valencia, Spain, in February 2021 during a month-long equestrian…

In a breakthrough in the global fight against malaria, the World Health Organization (WHO) is recommending widespread administration of the first-ever malaria vaccine. This first-generation vaccine is intended for children considered to be at high…

The diverse totality of microorganisms regularly found on and in the human body is collectively referred to as the human microbiota or microbial flora, with the largest microbial community in the body residing in the large intestine, or colon.…

In many animals, including humans, the sense of smell performs an important threat-detection function by helping to identify potential sources of harm, such as rotting food and toxic fumes. Little is known, however, about the initial neural…

The field of vaccination has been enhanced significantly by the successful development of two approved vaccines based on messenger RNA (mRNA) technologies. Prior to the COVID-19 pandemic that spread from China in 2019 to the rest of the world in…

On April 7, 2021, the U.S. Centers for Disease Control and Prevention (CDC) announced that a genetic variant of SARS-CoV-2—the coronavirus that causes COVID-19—that was initially identified in the United Kingdom is the dominant form of the virus…

In response to the COVID-19 (coronavirus disease 2019) pandemic—which has dramatically affected the entire world, causing high morbidity, mortality, and massive social and economic disruption—and in addition to finding efficacious treatments for…

Researchers at Northwestern University, Evanston, Illinois, USA, have developed a virus catcher of sorts—that is, a sticky and absorbent surface coating that traps droplets and aerosols (microdroplets) that land on the coating. Most often, fine…

There is a growing body of evidence that many of the thousands of prescription and over-the-counter medications ultimately make their way into water bodies and drinking-water supplies. Typical wastewater treatment plants may not be effective at…

Scientists have suggested a possible connection between ancient Neandertals (Homo neanderthalensis) and the severity of disease in patients affected by COVID-19. In short, certain genes acquired from Neandertals during instances of interbreeding…

The novel coronavirus SARS-CoV-2 that emerged in central China in late 2019 and subsequently spread across the world in 2020 led to the COVID-19 pandemic. The emergence of a previously unknown pathogen—such as the novel coronavirus—that could affect…

There has been substantial progress in the fight against certain drug-resistant organisms that cause serious, often fatal, diseases. However, two drug-resistant microbes—specifically, Candida auris (a fungal yeast) and Acinetobacter (a genus of…

Sickle cell disease, also termed sickle cell anemia, is a genetic disorder in which hypoxia, or oxygen deprivation, causes red blood cells (erythrocytes) to assume a rigid sickle shape, blocking blood flow within blood vessels. The disease results…

The earliest representatives of modern humans—those belonging to Homo sapiens—evolved from more archaic humans approximately 150,000–300,000 years ago in eastern Africa. During succeeding years, the geographical range of anatomically modern humans…

Mucus produced by the common garden snail (Helix aspersa) is green. The slime is not actually green in color but is “green” in terms of its environmentally friendly chemistry. It turns out that this snail’s mucus has chemical properties as a…

Heroin (C21H23NO5) is a white, crystalline powder synthesized from morphine, a natural alkaloid extracted from the seedpod of the Asian opium poppy plant, Papaver somniferum. It is a powerful opioid drug prepared by the addition of two acetyl groups…

The majority of toxic pollution in the United States could potentially be eliminated by requiring a small number of extreme polluters to release pollutants at levels in line with those of comparable industrial facilities, according to a recent study…

Over thousands of years of study of the human body through dissection and, more recently, modern-day imaging techniques, scientists have observed and analyzed various glands—that is, structures or organs that produce and secrete a substance or…

During the initial stages of the COVID-19 pandemic, most restaurants and other dining facilities were shut down to contain the spread of the SARS-CoV-2 virus. By July 2020, however, indoor dining once again became an option for many…

Since the start of the COVID-19 (coronavirus disease 2019) pandemic, doctors and epidemiologists have identified a number of underlying medical conditions that are significantly correlated with severe illness from COVID-19. One such notable…

As offices, schools, health clubs, restaurants, hotels, and other facilities gradually reopen after shutdowns related to the COVID-19 pandemic, the public may confront yet another unmitigated health hazard: unsafe water from dormant or underused…

Over the course of history, smallpox has been among the most feared diseases of humankind. Caused by the variola virus (a DNA-containing member of the Poxviridae family) and spread by transfer through respiratory droplets during face-to-face…

Occurring in mammary glands and closely associated tissues, breast cancer is the most common cancer observed in women. For example, in the United States, approximately 1 in 8 women (about 12%) will develop invasive breast cancer over the course of…

A form of ultraviolet (UV) light holds promise as an innovative way to neutralize airborne SARS-CoV-2 particles and other viruses, potentially helping slow the COVID-19 pandemic that, to date, has caused over 1.3 million deaths globally. More…

Poliomyelitis, more commonly called polio, is a devastating infectious disease of the central nervous system caused by the poliovirus (a type of enterovirus), which has three types in the wild (types 1, 2, and 3). Wild types 2 and 3 were declared…

Persistent changes in the Earth's climate that have been occurring primarily as a result of human-caused greenhouse-gas emissions since the mid-twentieth century have led to significant increases in infectious diseases in wildlife, both in terms of…

The Ebola virus comprises a group of pathogenic agents that cause severe and deadly hemorrhagic fevers in humans and other primates. During 2014 and 2015, an Ebola virus epidemic in West Africa—predominantly, the countries of Guinea, Liberia, and…

The cancer death rate in the United States has fallen by 27% since 1991. According to the American Cancer Society, which compiled the data over a 25-year period from 1991 to 2016, a total of 2.6 million fewer individuals have died from cancer in the…

A compound found in cranberries, called cranberry proanthocyanidin (cPAC), when used in combination with antibiotics, such as tetracycline, prevents resistance to antibiotics in Escherichia coli and Pseudomonas aeruginosa, according to researchers…

At the Woranso-Mille paleontological site in northern Ethiopia, researchers have discovered a 3.8 million-year-old cranium (skull) belonging to a primitive hominin known as Australopithecus anamensis. Initially unearthed in 2016, but not reported…

Eastern equine encephalitis is a rare infectious viral disease that primarily affects humans and equines (horses, mules, donkeys, and zebras). It is caused by a mosquito-borne virus (arbovirus) that is native to the eastern half of the United…

Fentanyl is a synthetic opioid analgesic (pain reliever) that resembles morphine in its action. However, its drug potency is approximately 50 to 100 times more powerful than that of morphine, leading to high rates of both addiction and overdose…

The four main blood types (blood groups) found in humans are A, B, AB, and O. Two particular antigens (A and B) determine the specific blood type—A antigen is present in type A blood; B antigen is present in type B blood; both A and B antigens are…

Researchers at Duke University in North Carolina (United States) have developed a test for distinguishing lead isotopes found in coal fly ash from lead isotopes found in other lead-containing sources, such as paint. Fly ash is a fine particulate…

Macular degeneration is the most prevalent cause of vision impairment and loss among people aged 55 years and older. Also termed age-related macular degeneration (AMD), this serious eye condition damages the macula, which is the most sensitive part…

Marburg hemorrhagic fever (also referred to as Marburg virus disease) is a rare, exotic viral disease that affects both humans and nonhuman primates. The reservoir hosts of Marburg virus are African (or Egyptian) fruit bats (Rousettus aegyptiacus),…

Measles is a highly infectious and communicable disease that is most often contracted in childhood. The infective particle is a ribonucleic acid (RNA) virus—specifically, a paramyxovirus belonging to the genus Morbillivirus. Infected individuals…

Caused by the rod-shaped bacterium Mycobacterium tuberculosis and transmitted by airborne droplets from a diseased individual, tuberculosis (TB) is a chronic infectious disease of humans (and other animals) that destroys body tissue. When M.…

Osteoprotegerin (OPG) is a protein that plays a central role in the regulation of bone mass. Also known as osteoclastogenesis inhibitory factor (OCIF), this naturally occurring protein [a soluble decoy receptor protein that belongs to the tumor…

The bacteria that live in the gut (gastrointestinal tract) constitute a large part of an individual's microbiome (also known as microbiota). In general, gut bacteria, also referred to as the microbial flora of the gut, are harbored by normal,…

Influenza is a viral disease that affects numerous animals, including birds, pigs, horses, and humans. It also can affect dogs, and epidemiologists are increasingly concerned about the potential transmission of the influenza virus from these animals…

Psychedelic drugs, also termed hallucinogenic or psychotomimetic drugs, induce transient states of altered perception resembling or mimicking the symptoms of psychosis and are characterized by profound alterations in mood. Because psychedelic drugs…

Statins comprise a group of drugs that are widely prescribed to combat high cholesterol. They suppress the production of cholesterol in the liver and interfere with the formation of plaques in the arteries of the body. As such, these…

Cannabidiol (CBD) is the predominant cannabinoid (chemical constituent) of the more than 100 cannabinoids found in the hemp variety of the plant Cannabis sativa. There are preliminary, yet unproven, claims that CBD may offer benefits for treating…

Those who fear contracting a water-borne illness caused by pollution at the shore or ingesting a killer amoeba (Naegleria fowleri) at a freshwater lake might instead opt to visit a swimming pool. After all, most pool water is hygienically treated.…

Researchers have developed polymeric materials that are able to kill multidrug-resistant bacteria without inducing drug resistance or toxic side effects, according to a report in Nature Communications (March 2018). The polymers, known as…

Antisense drugs are gene-based molecules that inhibit the synthesis of proteins (including proteins that cause specific diseases) by binding to the ribonucleic acids (RNAs) responsible for their formation. Specifically, these drugs are…

Soil harbors a vast reservoir of antimicrobial agents. In fact, approximately 80% of all clinically implemented antibiotics are derived from soil-dwelling bacteria. However, many bacteria have evolved methods to evade the effects of various…

The Asian longhorned tick (Haemaphysalis longicornis), also known as the bush tick, is a troublesome parasitic species and is an important vector of disease agents. (Note that vectors are capable of biologically transferring a pathogen from one…

In an application of green chemistry, researchers reported in the journal Biomaterials (April 2018) the caffeine-catalyzed synthesis of a new class of polymer gels for drug delivery and other biomedical applications. These caffeine-catalyzed gels…

Handheld electronic devices with plastic casings, such as cell phones, may be exposing users to toxic organophosphate ester (OPE) flame retardants that leach out of these products. Researchers from the University of Toronto reported in Environment…

Tuberculosis (TB) is a chronic infectious disease of humans (as well as animals) primarily involving the lungs. It is caused by the tubercle bacillus Mycobacterium tuberculosis and is transmitted by pathogenic airborne droplets. Approximately 5–10%…

CRISPR/Cas9 gene editing is a modern technique that targets specific stretches of genetic code and allows editing of deoxyribonucleic acid (DNA) at designated locations. It has been at the forefront of genetic research, providing scientists with the…

The influenza virus may be easier to transmit than previously thought, according to a report in the Proceedings of the National Academy of Sciences (January 2018). It turns out that sneezing and coughing are not required to pass on the influenza…

The prevalence of diseases caused by ticks, mosquitoes, and fleas that feed on the blood of humans has increased dramatically. Over a 13-year span (the years 2004 through 2016), the incidence of tick-, mosquito-, and flea-borne diseases in humans…

A new single-dose antiviral drug can shorten the duration of the flu in teens and adults by about a day, according to a study published in the New England Journal of Medicine (September 2018). The drug, baloxavir marboxil (Xofluza™; baloxavir),…

Autism, also known as autism spectrum disorder (ASD), is a complex neurodevelopmental condition that impairs the way that a person relates to and communicates with other people. In addition, autism is characterized by restricted, repetitive, or…

Regeneration is the regrowth and replacement of living tissues or organs that have been lost or severely injured through mishaps or disease. The goal of regenerative medicine with regard to humans is to restore the structure and function of any…

To better understand the nutritional effects (health benefits), chemical composition, growing conditions, and shelf life of microgreens, a team of researchers reviewed the science behind them in the Journal of Agricultural and Food Chemistry…

It is estimated that 1 gram of soil can be inhabited by up to 109 microorganisms and approximately 60,000 bacterial species. Moreover, soil harbors a vast reservoir of antimicrobial agents, and soil-dwelling bacteria have played a key role in the…

Colorectal cancer (also termed colon or bowel cancer) is the third most prevalent type of cancer both in men and in women, taking the lives of approximately 400,000 people annually worldwide (including 50,000 people per year in the United States).…

There are 27 ways a heat wave can kill you, according to a report in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes (November 2017). By 2100, at the current rate of greenhouse-gas emissions, three-quarters of…

The biotechnology used in the creation of genetically modified crops is being expanded to encompass the bioengineering of plants that contain therapeutically important proteins and molecules that can be utilized in the manufacturing of…

Experimental trials in Guinea, West Africa, confirmed the efficacy of an Ebola virus vaccine, according to a report by World Health Organization (WHO) scientists published in late 2016. The vaccine known as rVSV-ZEBOV (recombinant vesicular…

The water crisis that gripped the city of Flint, Michigan, in 2014 and 2015—and which is still felt to the present day—became one of the most notorious and scandalous public health disasters in recent United States history. The immediate cause was…

Survival prospects for the honeybee (Apis mellifera) look increasingly promising as entomologists and beekeepers have reported a dramatic increase in the population numbers of these essential insects in North America and Europe. Honeybees, which are…

A new species of orangutan has been identified in the Batang Toru forest ecosystem in northern Sumatra, Indonesia. Genetic and morphological evidence, as well as behavioral data, have confirmed that the Tapanuli orangutan (Pongo tapanuliensis) is…

In recent years, Brazil has been faced with outbreaks of a variety of perilous viral diseases, especially Zika virus disease, dengue fever, and yellow fever. Now, medical personnel and researchers are troubled by another emerging virus disease known…

The human immunodeficiency virus (HIV) is a retrovirus that attacks and compromises the body's immune system, resulting in affected individuals facing long-term debilitating health. Without treatment, HIV-infected individuals typically succumb to…

New regulations by the U.S. Food and Drug Administration (FDA) that went into effect on January 1, 2017, banned the use of antibiotics as feed supplements to help livestock and poultry grow faster. The new rules, prohibiting the over-the-counter…

Surface water from streams across the United States contain a diverse mixture of synthetic organic pollutants, according to a joint U.S. Geological Survey (USGS) and U.S. Environmental Protection Agency (EPA) study reported in the journal…

The benefits of outdoor physical activity (exercise) outweigh the potential harm caused by air pollution except in the most highly polluted cities, according to epidemiological studies reported in the journal Preventive Medicine (February 2016).…

Cafestol, C20H28O3, is a compound, specifically a diterpene alcohol, found in coffee beans. It is extracted during the coffee-brewing process and may be present in coffee beverages, depending on the preparation method. Consumption of cafestol in…

Mosquito repellents are natural and synthetic chemical compounds that are applied to skin, clothing, and sometimes home furnishings such as bed nets. For years, they have been an important defense against mosquito-borne diseases, such as Dengue…

Ebola virus disease is one of the most lethal and feared diseases in the modern world even though the total number of people harmed by it throughout history is, fortunately, far smaller than for better known scourges such as malaria and influenza.…

The emergent discipline of evolutionary epidemiology recognizes that pathogens (disease-causing organisms) are biological entities that can evolve quickly to take advantage of ecological or environmental changes that promote their transmission.…

Organic micropollutants are synthetic chemicals found in water sources and treated wastewater at concentrations in the range of micrograms per liter or lower. Micropollutants tend to be resistant to biodegradation and many are bioactive. Most…

Marfan syndrome (or Marfan's syndrome) is a connective-tissue disorder that manifests through distinctive skeletal and ocular changes as well as congenital heart disease. A mutation in the gene (FBN1) that normally directs the body to make…

The species diversity and ultimate survival of amphibians, one of the major groupings of vertebrate animals, face tremendous challenges today for reasons that are still not entirely understood. Since the 1980s, the pace of amphibian extinction has…

Biodegradable metals, also known as bioresorbable or bioabsorbable metals, are compatible with human tissues and degrade to nontoxic by-products. The most promising candidates for use as orthopedic and cardiovascular implants are alloys of…

Biologic drugs, also known as biologics or biologicals, are produced using living organisms. Various classic biologics, such as the medical human insulin taken by diabetics, have been made by biotechnology processes for some decades. What is…

In the Rising Star cave system in South Africa, located about 48 kilometers (30 miles) north of Johannesburg, paleoanthropologists have unearthed an extensive collection of more than 1550 skeletal elements from at least 15 individuals that have…

Lobsters are bottom-dwelling decapod crustaceans making up the family Nephropidae (also called Homaridae). The most familiar and commercially important lobsters are large-clawed ones possessing a hard protective exoskeleton and belonging to the…

Homeopathy (homeopathic medicine) is one of the most commonly used forms of complementary or alternative medical treatment around the world, in part because its remedies are nontoxic and typically inexpensive. Yet it also has no sound scientific…

In the Afar region of Ethiopia, paleoanthropologists unearthed a 2.8 million-year-old jawbone (mandible) that was provisionally assigned to the genus Homo [the genus of human beings, including modern humans (Homo sapiens) and other extinct species].…

Phthalates are esters of 1,2-benzenedicarboxylic acid (phthalic acid) [1] made by reacting phthalic anhydride (2) with alcohols. Phthalates are used mostly as plasticizers—additives to make ridged polymers flexible. Flexible poly(vinyl chloride), or…

Researchers have discovered an antimalarial compound that shows promise for killing the deadliest malaria parasite, Plasmodium falciparum, at multiple stages of its life cycle. High-throughput screening of more than 4700 molecules yielded an…

The increasing resistance of many common disease-causing bacteria to antibiotics poses a global health crisis. However, a powerful compound called teixobactin, belonging to a new class of antibiotics (specifically, a novel class of peptidoglycan…

The ancient Egyptian civilization flourished along the banks of the Nile River, which supplied the waters that ensured a prosperous and lengthy agricultural vitality over the course of thousands of years. On the strength provided by this rich…

The Aztecs were an indigenous group of Mesoamerican tribal peoples whose influence dominated that region between the fourteenth and early sixteenth centuries. They predominantly spoke a native language called Nahuatl, and they lived a nomadic…

The Babylonian civilization flourished from approximately 1900 to 539 BC in the central and southern regions of Mesopotamia (present-day Iraq), predominantly between the Euphrates and Tigris rivers. Before the rise of the Babylonians, the area was…

Recycling or reuse is in most instances environmentally preferable to disposal. Reuse of coal tar as an asphalt-pavement sealant for driveways and parking lots, however, has turned out to be an exception to this rule of thumb. Asphalt and asphaltite…

The evolutionary ancestry of the modern human race became even more complicated in 2012 with the results of studies on DNA extracted from bits of 50,000-year-old bone from Siberia. The analysis confirmed that an archaic species of people called…

The U.S. Food and Drug Administration (FDA) on November 22, 2013 approved the first H5N1 avian influenza (bird flu) adjuvanted vaccine for adults. An adjuvant is a substance added to a vaccine that stimulates the body's immune response to an…

The Incas were a group of native South American people who created an empire that was the largest civilization in the New World prior to the arrival of Columbus. The early Incas predominantly inhabited the highlands of the central Peruvian Andes.…