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The 1903 Flyer was the first aircraft to make a successful, controllable, heavier-than-air flight. View the Flyer at different angles, the customized lightweight motor, and other related images for a complete picture of this breakthrough in aircraft…

An early mechanical calculator. The abacus likely originated in Babylonia sometime before 1000 BCE. Over the subsequent centuries, it became a commonplace device in many regions of the world. The abacus is still occasionally used as a cognitive…

The net movement (transport) of water and solutes from outside an organism to its interior. The unidirectional flow of materials into an animal from the environment generally takes place across the alimentary tract, the lungs, or the skin. In each…

The time rate of change of velocity. Acceleration is a physics term that measures the rate of change of velocity per unit of time. Because velocity is a directed or vector quantity involving both magnitude and direction, a velocity may change by a…

The technique of measuring the magnitude and direction of acceleration. Measurement of acceleration (see illustration) includes translational acceleration with tangential and radial components and angular acceleration. Acceleration The May 16, 2011…

A chemical compound, (CH3)2CO; the first member of the homologous series of aliphatic ketones. Acetone (see illustration) is a colorless, volatile, and flammable liquid. Acetone occurs naturally in plants and animals. Its physical properties include…

One of a large group of organic substances possessing the halocarbonyl group in which X stands for fluorine, chlorine, bromine, or iodine. The terms acyl and aroyl halides refer to aliphatic or aromatic derivatives, respectively.The great inherent…

An instrument that utilizes focused acoustic waves to produce images of surface and subsurface features in materials, and to measure elastic properties on a microscopic scale. It has been used to image and measure local elastic properties in metals,…

Unwanted sound. Noise control is the process of obtaining an acceptable noise environment for people in different situations. These definitions and the words “unwanted” and “acceptable” suggest that criteria need to be established to determine when…

The discipline of acoustic phonetics can be narrowly defined as the study of the acoustic output of the vocal tract for speech, but ultimately it encompasses much more. Acoustic phonetics makes direct contact with, and in many cases is the…

A device to measure the acoustic power or intensity of a sound beam by means of the force or torque that the beam exerts on an inserted object or interface. The underlying theory involves the concept of radiation pressure, which is the…

A discipline that deals generally with the extraction of information from acoustic signals in the presence of noise and uncertainty. Acoustic signal processing has expanded from the improvement of music and speech sounds and a tool to search for oil…

A type of connective tissue, especially in mammals, that is specialized for the storage of neutral fats (lipids). Adipose cells originate mainly from fibroblasts (connective tissue cells found in virtually all animal organs). In the mammalian…

The ratio of the current to the voltage in an alternating-current circuit.In terms of complex current I and voltageV, the admittance of a circuit is given by Eq. (1), and is related to the impedance of the circuit Z by Eq. (2). Y is a complex number…

A group of software development methods in which requirements and solutions evolve through collaboration between the developers and the customers. Agile methods have significantly changed the practice of software development since their inception…

A branch of meteorology that examines the effects and impacts of weather and climate on crops, rangeland, livestock, and various agricultural operations. Agricultural meteorology, or agrometeorology, addresses topics that often require an…

The pure and applied science that is concerned with botany and management of crop and ornamental plants for utilization by humankind. As it relates to plants, agricultural science concerns itself with the application of scientific methods to…

The art and science of crop and livestock production. In its broadest sense, agriculture comprises the entire range of technologies associated with the production of useful products from plants and animals, including soil cultivation, crop and…

The science and study of crops and soils. Agronomy is the umbrella term for a number of technical research and teaching activities (see illustration): crop physiology and management, soil science, plant breeding, and weed management frequently are…

A discipline that combines the means to know the location and heading of an aircraft with respect to some map or coordinate system, with guidance which means steering the aircraft along some desired path toward a destination. The construction of the…

Natural and artificial substances in the atmosphere that affect human health or well-being, or the well-being of any other organisms in the environment. Air pollution also applies to situations in which contaminants affect structures and artifacts…

An informal assemblage of predominantly aquatic organisms that carry out oxygen-evolving photosynthesis, but lack specialized water-conducting and food-conducting tissues. Algae (Fig. 1) may be either prokaryotic organisms (lacking an organized…

The branch of mathematics dealing with the solution of equations. These equations involve unknowns, or variables, along with fixed numbers from a specified system (Fig. 1). The origins of algebra were based on the need to develop equations that…

Any compound having highly basic properties, strong acrid taste, and ability to neutralize acids. Aqueous solutions of alkalies are high in hydroxyl ions, have a pH above 7, and turn litmus paper from red to blue. Caustic alkalies include sodium…

The elements of group 1 in the periodic table. Of the alkali metals, lithium differs most from the rest of the group, and tends to resemble the alkaline-earth metals (group 2 of the periodic table) in many ways. In this respect lithium behaves as do…

Usually calcium, strontium, and barium, the heaviest members of group 2 of the periodic table (excepting radium). Other members of the group are beryllium, magnesium, and radium, sometimes included among the alkaline-earth metals. Beryllium…

A natural process in which harmful or beneficial effects are caused by secondary metabolites that spread from a donor organism to a recipient and are produced by plants, algae, bacteria, and fungi. Allelopathy is a key ecological process and has…

A regulatory enzyme whose activity is modified by the binding of an activator molecule to an alternate (allosteric) site that is different from the active (catalytic) site. Allosteric enzymes (Fig. 1) are special enzymes involved in regulatory…

A metal product containing two or more elements as a solid solution, as an intermetallic compound, or as a mixture of such metallic and/or nonmetallic phases. This article will describe alloys on the basis of their technical applications. Alloys may…

Substances formed by the addition of one or more elements, usually metals, to aluminum. The principal alloying elements in aluminum-base alloys are magnesium (Mg), silicon (Si), copper (Cu), zinc (Zn), and manganese (Mn). In wrought products, which…

A disease of the nervous system characterized by a progressive dementia that leads to profound impairment in cognition and behavior. Dementia occurs in a number of brain diseases where the impairment in cognitive abilities represents a decline from…

Any of a group of drugs of diverse chemical structure and physiological effects that are used for the relief of pain. Analgesics are drugs, including opiates, synthetic opioids, and salicylates, that are used primarily for pain relief (see…

The closest spiral galaxy to the Milky Way Galaxy. The name of the Andromeda Galaxy (Fig. 1) derives from its appearance in the constellation of Andromeda. The galaxy is also known as M31 and NGC 224, based on its entries in two widely used…

The analog of linear momentum for rotational motion. A particle with mass m moving with velocity v has linear momentum p = m v (Note: This article follows the convention of using bold, non-italicized variables for vectors and using non-bold,…

Any living organism taxonomically assigned to the classification kingdom known as Animalia. Members of the kingdom Animalia—that is, animals (see illustration)—possess certain characteristics that distinguish them from organisms belonging to the…

The processes of biological and organic change in animals by which descendants come to differ from their ancestors. Animal evolution encompasses the theory that modern animals are the modified descendants of animals that formerly existed and that…

A psychiatric disorder in which a dramatic reduction in caloric intake consequent to excessive dieting leads to significant bodily, physiological, biochemical, emotional, psychological, and behavioral disturbances. Anorexia nervosa is one of three…

An ongoing current event in which a large number of living species are threatened with extinction or are going extinct because of environmentally destructive human activities. The Earth is presently in the midst of a mass extinction event. In the…

A chemical substance, produced by microorganisms, plants, marine organisms, and synthetically, that has the capacity in dilute solutions to inhibit the growth of bacteria or destroy bacteria. Antibiotics are important antibacterial agents. Most are…

The capability that a bacterium acquires to counteract an inhibitory chemical molecule or compound that was formerly effective in killing it or preventing its growth. Antibiotic resistance in bacteria (Fig. 1) is a hot topic in the media and in…

A protein, found principally in blood serum, originating normally or in response to an antigen and characterized by a specific counteracting reactivity with that antigen. Antibodies (Fig. 1) are members of the immunoglobulin class of proteins and…

Any substance that causes the immune system to produce specific antibodies or T cells against it. An antigen may be a foreign substance from the environment (such as chemicals, bacterial or viral proteins, or pollen; Fig. 1) or formed within the…

A reaction that occurs when an antigen combines with a corresponding antibody to produce an immune complex. A substance that induces the immune system to form a corresponding antibody is called an immunogen. All immunogens are also antigens because…

Chemical compounds biosynthetically or synthetically produced that destroy or usefully suppress the growth or metabolism of a variety of microscopic or submicroscopic forms of life. On the basis of their primary activity, antimicrobial agents (see…

A group of distinct psychiatric disorders including generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, specific phobia, and posttraumatic stress disorder. Whereas fear is an adaptive emotion that is…

An order of leeches (subclass Hirudinida) characterized by the absence of a protrusible proboscis and including both blood-feeding and macrophagous (predatory) varieties. Most notorious among the blood-feeding leeches in the Arhynchobdellida is the…

A group of diseases affecting joints or their component tissues. Arthritis is the collective term used to describe any joint disorder or process; it also typically involves inflammation. In common usage, arthritis often refers to any joint pain.…

Vegetables that are prevalent in Asian cuisines, but less well known in Western diets. Asian vegetables (Fig. 1), also referred to as Asian greens or oriental vegetables, are very important in Asian countries, but are not as popular in North America…

A white, crystalline compound, 1-aspartyl-1-phenylalanine methyl ester (APM), used as an artificial sweetener. Aspartame is composed of two amino acids: aspartic acid and phenylalanine [structure (1)]. Amino acid Artificial sweetener Aspartame…

Any treatment or procedure that includes the in-vitro handling of oocytes (immature ova or egg cells) and sperm or embryos for the purpose of establishing a pregnancy. Assisted reproductive technology (ART) is undertaken as a treatment of…

A class of the asterozoan group of the phylum Echinodermata, often known as sea stars or starfish. Members of the class Asteroidea, that is, asteroids, are notable echinoderms with a star-shaped body plan (Fig. 1). Unlike members of their sister…

An analytical technique for determining the composition of a sample in terms of the chemical elements present and their quantities or concentrations. Unlike other methods of elemental analysis, however, the sample is decomposed into its constituent…

The most common type of arrhythmia (any disorder of the heart rate or rhythm). Atrial fibrillation, often abbreviated AFib or AF, is a heart condition that can lead to potentially serious complications. It is associated with decreased quality of…

A neurodevelopmental condition that impairs the way that a person relates to and communicates with other people. Persons with autism have difficulties with social communication and interaction. They also can have unusual behaviors, such as…

The processes of both the increase in number and the increase in mass of bacteria. The net growth in a population of bacteria (Fig. 1) depends on its ability to produce new biomass, to produce new cells incorporating that biomass, and to survive…

The management and maintenance of colonies of honeybees for human purposes. Beekeeping is an ancient art. Although the commonly known honeybee species (Fig. 1) is native to Europe and Africa, humans have transported them to other continents. The…

A fermented beverage produced from grain. Beer is a generic term used to describe alcoholic beverages made from cereal grains, especially barley (Fig. 1), in the form of malt. Ale, lager, porter, and stout are different kinds of beer made by…

An organic acid, C6H5COOH; also known as benzene carboxylic acid. Benzoic acid is a crystalline solid, with the structure below. Benzoic acid has a melting point of 122°C, and sublimes at 100°C. Benzoic acid is only slightly soluble in water but is…

A chemical element, chemical symbol Be, atomic number 4, and atomic weight 9.0122. Beryllium is the first element in the group called alkaline-earth metals on the periodic table (Fig. 1). Alkaline-earth metals Atomic number Chemical element Periodic…

The study of the substances and chemical processes that occur in living organisms. Biochemistry is a shortening of the term biological chemistry. It is a scientific discipline that investigates the chemical compounds and reactions that take place…

The destruction of organic compounds by microorganisms. Biodegradation is a process (carried out by microorganisms) that decomposes organic material into its constituent elements or new compounds. Microorganisms, particularly bacteria (and fungi to…

A microbial (often bacterial) community that is enveloped by an adhesive substance (the glycocalyx) at the interface of a liquid and a surface. Biofilms (see illustration) are defined as highly structured communities of microorganisms that are…

The study of the cycling of chemicals between organisms and the surface environment of the Earth. The chemicals either can be taken up by organisms and used for growth and synthesis of living matter or can be processed to obtain energy. The chemical…

The use of parasitoids, predators, and pathogens to reduce injurious pest insect populations and consequently the damage that they cause. Biological insect control (or insect biocontrol) is the regulation of insect populations by biological means.…

The emission of light by living organisms that is visible to other organisms. Bioluminescence (see illustration) does not come from or depend on light absorbed by the organism. It derives from an enzymatically catalyzed chemiluminescence, that is, a…

The application of principles from applied and physical sciences to problems in healthcare and biology. As a field, biomedical engineering draws from a variety of disciplines including mechanical, chemical, electrical, and computer engineering, as…

A form of terrorism in which there is the intentional release of biological agents (viruses, bacteria, fungi, or toxins) from living organisms or agents in order to cause death or disease in humans, animals, and/or plants; also referred to as…

A binary digit. In the computer, electronics, and communications fields, “bit” is generally understood as a shortened form of “binary digit.” In a numerical binary system, a bit is either a 0 or 1. Bits are generally used to indicate situations that…

One of the main extant classes in the phylum Mollusca. Members of the molluscan class Bivalvia (formerly, Pelecypoda) are known commonly as bivalves and include clams, oysters, mussels, and scallops. All bivalves are aquatic, living at all depths of…

A fluid connective tissue that circulates in the vascular system (blood vessels) of the body. Blood circulates through the body via vascular blood vessels (arteries, veins, and capillaries). Blood consists of plasma (the fluid component) and cells…

Any of the tubular channels for blood transport, of which there are three principal types: arteries, capillaries, and veins. Blood circulates through the body via blood vessels, which include the arteries, veins, and capillaries. These structures…

In glass blowing, a long straight tube on which molten glass is gathered and worked, partly by blowing into the tube. The blowpipe (see illustration) is spun to shape the glass object further by centrifugal force, or by a tool, in which case the…

A genus of pathogenic gram-negative bacteria that are coccobacilli and obligate aerobes, and fail to ferment carbohydrates. Bordetella bacteria are respiratory pathogens. Bordetella pertussis, B. parapertussis, and B. bronchiseptica share greater…

A subprocess of welding encompassing a group of process embodiments in which coalescence is produced by heating to suitable temperatures above 450°C and by using a filler metal that must have a liquidus temperature above 450°C and below the solidus…

Assembling an electronic circuit in the most convenient manner on a board or other flat surface, without regard for final locations of components, to prove the feasibility of the circuit and to facilitate changes when necessary. Standard breadboards…

The potential difference at which an electrically stressed gas is tranformed from an insulator to a conductor. In an electrically stressed gas, as the voltage is increased, the free electrons present in the gas gain energy from the electric field.…

Either of the two human mammary glands, usually well developed in the adult female, but rudimentary in the male. Breast is the common term used for the human mammary gland. This structure is particularly important in the adult female because it…

A circuit composed of a source and four impedances that is used in the measurement of a wide range of physical quantities. The bridge circuit is useful in measuring impedances (resistors, capacitors, and inductors) and in converting signals from…

Electronic circuits whose primary function is to connect a high-impedance source to a low-impedance load without significant attenuation or distortion of the signal. Thus, the output voltage of a buffer replicates the input voltage without loading…

Unwanted, aggressive behavior that involves a real or perceived power inequity. The behavior of bullying is often chronic and includes actions such as threats, spreading rumors, attacking someone physically or verbally, and purposefully excluding or…

The reaction that occurs when tissue (usually skin) receives more energy (heat, chemical energy, electrical energy, or radiation) than it can absorb without injury. Factors such as the duration of contact, temperature, volume of chemical, and…

The velocity at which the combustible gases move through a flame in the direction perpendicular to the flame surface defines the burning velocity. The term flame as used here refers to the burning of combustible gases. The process of combustion, or…

An aluminum or copper conductor supported by insulators that interconnects the loads and the sources of electric power in an electric power system. A typical application is the interconnection of the incoming and outgoing transmission lines and…

A removable metal lining, usually in the form of a bearing to carry a shaft. Generally a bushing is a small bearing in the form of a cylinder and is made of soft metal or graphite-filled sintered material. Bushings are also used as cylindrical…

A system that receives and processes television signals, as well as other digital forms of communications such as those related to high-speed Internet connectivity and cable telephony, from various sources and retransmits these signals through…

The testing of electric circuits to determine and locate any of the following circuit conditions: (1) an open circuit, (2) a short circuit with another conductor in the same circuit, (3) a ground, which is a short circuit between a conductor and…

Desktop or, more often, portable electronic devices that are used to perform arithmetic, statistical, or other, more complex processing operations at the step-by-step direction of the user or by execution of a program (a stored sequence of…

Cells within a tumor that possess the capacity to self-renew and cause the heterogeneous lineages of cancerous cells that comprise the tumor. Cancer stem cells (CSCs) typically represent a small percentage of all cells in a tumor (rarely more than…

A genus comprising yeasts that cause a variety of human diseases referred to as candidiasis. All Candida species are single-celled yeasts (fungal organisms) that are ovoid in shape and 3–5 μm in size, and they multiply by a process called budding.…

A broad designation for a class of solid carbon-based materials with high elemental carbon content produced from the thermal decomposition of hydrocarbons. Carbon black can be produced with a range of physical properties tailored to applications.…

A heart-shaped curve generated by a point of a circle that rolls (without slipping) on a fixed circle of the same diameter. In point-wise construction of the curve, let O be a fixed point of a circle C of diameter a, and Q a variable point of C. Lay…

A periodic waveform upon which an information-bearing signal is impressed. This process is known as modulation and comprises a variety of forms such as amplitude, phase, and frequency modulation. The most common type of carrier is the sinusoidal…

An amplifier stage consisting of a common-emitter transistor cascaded with a common-base transistor. The common-emitter–common-base (CE-CB) transistor pair constitutes a multiple active device which essentially corresponds to a common-emitter stage…

The formation of vapor- or gas-filled cavities in liquids. If understood in this broad sense, cavitation includes the familiar phenomenon of bubble formation when water is brought to a boil under constant pressure and the effervescence of champagne…

An enclosure capable of resounding or resonating and thereby intensifying sound tones or electromagnetic waves. Resonance is the phenomenon which results when the frequency of the impressed driving force is the same as the natural vibration of the…

A set of four numbers used to specify the orientation of a body, or equivalently, the rotation R which produces that orientation, starting from some reference orientation. They can be expressed in terms of the Euler angles ψ, θ, and ϕ, as in Eqs.…

An autoimmune disorder caused by gluten sensitivity that damages the small intestine and leads to the malabsorption of nutrients from food. Celiac disease (CD) is an autoimmune condition of the small intestine that is believed to be T-cell…

A cellular automaton is a hypothetical computer constructed of a regular array of cells that interact with neighboring cells according to a set of simple rules. Though conceptually simple, cellular automata can produce complex and surprising…

Mitosis is the series of visible changes that occur in the nucleus and chromosomes of non-gamete-producing plant and animal cells as they divide. This Image Gallery exhibit depicts these events using state-of-the art microscopy and digital image…

A fixed point in a body of matter through which the resultant force of gravitational attraction acts. The center of gravity is an imaginary point in any given body that is convenient when performing calculations and conducting mechanical studies…