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from article Amino acid
Structural formula for an amino acid. (Copyright © McGraw Hill)
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Image
from article Amino acid
The 20 amino acids that serve as the building blocks for proteins. These amino acids (shown with their respective three-letter abbreviations) can be divided into nonpolar, polar, and electrically charged groups. (Copyright © McGraw Hill)
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from article Amino acid
Synthesis of a dipeptide. When an amino group of one amino acid is linked to the carboxyl group of another amino acid, a peptide bond linkage is formed. A molecule of water (H2O) is split out when a peptide bond is formed. (Copyright © McGraw Hill)
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from article Amino acid
Two-dimensional chromatogram of a protein. (Credit: R. J. Block, E. L. Durrum, and G. Zweig)
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from article Mitochondrial replacement therapy
Spindle transfer involves the excision of the metaphase II spindle from a donor egg and replacing it with the metaphase II spindle from the affected egg. The metaphase II spindle contains the condensed chromosomes of the egg's haploid genome. Terms:…
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from article Mitochondrial replacement therapy
Cytoplasmic transplantation involves the addition of a donor's ooplasm (cytoplasm in an oocyte) to the recipient oocyte prior to fertilization. Terms: ICSI, intracytoplasmic sperm injection; mtDNA, mitochondrial DNA; nDNA, nuclear DNA. (Credit:…
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from article Mitochondrial replacement therapy
Pronuclear transfer requires that both the donor and affected eggs be fertilized by the father's sperm simultaneously in vitro. Following fertilization and once pronuclei are visible by microscopy, the two pronuclei from the donor egg are removed,…
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from article Tuberculosis
Tuberculosis is caused by the tubercle bacillus Mycobacterium tuberculosis. (Left) Colorized scanning electron micrograph (SEM) depicting some of the ultrastructural details seen in the cell wall configuration of a number of Gram-positive…
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from article Tuberculosis
Annual number of tuberculosis (TB) cases in the United States from 1992 to 2017. During this time period, there has been a decline in the prevalence of tuberculosis. However, the progression of decline has slowed since 2013 (indicated by the purple…
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from article Tuberculosis
Skin testing for tuberculosis, using the Mantoux test. (a) Tuberculin PPD (purified protein derivative) is injected into the dermis. A small bleb develops, but is absorbed within a short time. (b) After 48–72 h, the skin reaction is read and given a…
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from article Tuberculosis
Chest radiograph (posteroanterior view) showing extensive tuberculosis with cavitation in the right lung. (Copyright © McGraw-Hill Education)
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from article Oncology
Magnetic resonance imaging (MRI) of a human brain showing a tumor. The bright blue color indicates the location where the brain cancer metastasizes in the occipital lobe. (Credit: Leon Kaufman, University of California, San Francisco/National Cancer…
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from article Oncology
Human malignant osteosarcoma (bone cancer) cells taken from a leg mass. (Credit: Lance Liotta/National Cancer Institute)
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from article Oncology
Light micrograph of an adenocarcinoma of the colon. The tumor cells have made several acini, containing mucinous material and inflammatory cells. (Credit: Steve Gschmeissner/Science Photo Library/Alamy Stock Photo)
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from article Oncology
Light micrograph of a section through a squamous carcinoma of the skin. Whorls of enclosed keratin (green, center left) are a common feature. (Credit: Steve Gschmeissner/Science Photo Library/Alamy Stock Photo)
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from article Oncology
Gompertzian growth kinetics. (a) Growth fraction declines exponentially over time. (b) Growth rate of a tumor, which is a measure of the absolute number of dividing cells plotted as a function of time. (c) Tumor size as a function of time.
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from article Vitamin D
Conversion of vitamin D to its active form (1α,25-dihydroxyvitamin D3) in the human body. Vitamin D3 can be produced in skin by the ultraviolet irradiation of 7-dehydrocholesterol. It also can be obtained from the diet. (Copyright © McGraw-Hill…
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from article Tumor
Light micrograph of malignant tumor cells in colon tissue. The cancerous tumor cells have made several acini (saclike structures) containing mucinous material and inflammatory cells. (Credit: Steve Gschmeissner/Science Photo Library/Alamy Stock…
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from article Tumor
Colored magnetic resonance imaging (MRI) scan of an axial section through the brain showing a metastatic tumor (colored red and yellow). Metastatic cancer is a secondary disease spread from cancer elsewhere in the body. Metastatic brain tumors are…
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from article Clinical pathology
A disk diffusion antimicrobial susceptibility plate is used by clinical pathologists to assess antibiotic action by measuring zones of inhibition surrounding antibiotic-impregnated filter paper disks.
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from article Clinical pathology
Clinical pathology laboratory at Christus Santa Rosa Hospital, San Antonio, Texas, 1923.
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from article Clinical pathology
Overview of an automated chemical analysis system. Specimen racks are placed on a movable track that moves sequentially through sampling, read-out, and reporting stations in the course of multitest analyses.
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from article Clinical pathology
Microscopic examination of a stained peripheral blood smear. The field of view used for cell identification observed by the microscopist is projected on the monitor screen located behind the microscope.
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from article Clinical pathology
Capillary electrophoresis is used for DNA sequencing. Data are processed by a computer, which then converts the findings into a graphic display. This information is used to identify mutations, deletions, and insertions relating to human disease.
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from article Clinical pathology
Examination of an agarose gel with an ultraviolet light source to identify diagnostic fragments of DNA.
