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from article Microtechnique
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from article Microtechnique
Materials and method for applying cover slip to balsam wholemount. (a) Correct way; notice that the cover slip is held vertically centered over the drop of balsam. (b) Wrong way; this method draws the object to one side. (After P. Gray, Handbook of…
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from article Microtechnique
Making a smear preparation. (a) Place the drop about 1 in. (2.5 cm) from end of slide. (b) Apply a second slide just in front of the drop. (c) Push slide smoothly forward to spread the smear. (After P. Gray, Handbook of Basic Microtechnique, 3d ed.,…
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from article Microtechnique
Rotary microtome produced by the American Optical Co. (From P. Gray, Handbook of Basic Microtechnique, 3d ed., McGraw-Hill, 1964)
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from article Microtechnique
Method of mounting the wax block on the block holder. (After P. Gray, Handbook of Basic Microtechnique, 3d ed., McGraw-Hill, 1964)
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from article Microtechnique
Basic steps in cutting and mounting paraffin ribbons prior to staining. (a) Starting the ribbon. (b) Cutting the ribbon in lengths. (c) Mounting the dry ribbon. (d) Flooding the ribbons. (e) Warming the flooded ribbons to flatten them. (After P.…
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from article Microtechnique
Coplin jars for starting a slide through the reagent series. (After P. Gray, Handbook of Basic Microtechnique, 3d ed., McGraw-Hill, 1964)
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from article Absorption
Incident sunlight is absorbed, reflected, and scattered by tree leaves. (Credit: Shutterstock / photolinc)
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from article Capricornus
Modern boundaries of the constellation Capricornus, the Sea Goat. The celestial equator is 0° of declination, which corresponds to celestial latitude. Right ascension corresponds to celestial longitude, with each hour of right ascension representing…
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from article Bioorganic chemistry
Vancomycin and an analog that is active against vancomycin-resistant bacteria.
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from article Bioorganic chemistry
Foldamers that mimic proteins.
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from article Bioorganic chemistry
The rate of this intramolecular lactonization, relative to that of intermolecular esterification, mimics the rate increase caused by an enzyme's binding and orienting substrates for a bimolecular reaction.
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from article Bioorganic chemistry
Intramolecular models of enzymatic general acid and general base catalysis. (a) Intramolecular general acid catalysis causes this acetal to hydrolyze at pH 7 more than 107 times faster than the corresponding acetal without the carboxylic acid group.…
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from article Bioorganic chemistry
An antibody raised against the phosphonate analog of a tetrahedral intermediate catalyzes the hydrolysis of cocaine to ecgonine methyl ester.
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from article Bioorganic chemistry
A functionalized cyclodextrin mimics the enzyme RNase by catalyzing the regioselective hydrolysis of a model phosphodiester.
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from article Bioorganic chemistry
Enzyme-catalyzed reactions that have been commercialized as industrial processes.
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from article Bioorganic chemistry
Mechanism of DNA scission by calicheamicin. Reductive or nucleophilic cleavage of the trisulfide triggers conjugate (Michael) addition to the enone, rehybridization of the bridgehead carbon, and Bergman cyclization of the enediyne, generating a…
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from article Negative temperature
Populations (n) of states of a thermodynamic system consisting of N magnetically interacting nuclei of spin 2 at absolute temperatures T = +D/k and T = −D/k, where k is Boltzmann's constant and D is the energy spacing between successive states.
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from article Type 1 diabetes
One characteristic feature of type 1 diabetes is glomerulosclerosis (Kimmelstiel-Wilson lesion), which involves the scarring or hardening of the glomeruli (blood vessels) in the kidneys. (Copyright © McGraw-Hill Education)
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from article Type 1 diabetes
Stages in the development of type 1 diabetes. (Credit: Type 1 Diabetes TrialNet)
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from article Parathyroid gland
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from article Parathyroid gland
Common positions of human parathyroid glands on the posterior aspect of the thyroid. (After W. H. Hollinshead, Anatomy of the endocrine glands, Surg. Clin. N. Amer., 32(4):1115–1140, 1952)
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from article Parathyroid gland
Section of human parathyroid gland, demonstrating the two main parenchymal cell types. Zenker-formal fixation, Mallory-azan stain. (After D. Bloom and D. W. Fawcett, A Textbook of Histology, 9th ed., Saunders, 1968)
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from article Parathyroid gland
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from article Geotechnical engineering
Mike O'Callaghan-Pat Tillman Memorial Bridge over the Colorado River at the Hoover Dam, spanning Nevada and Arizona, USA. Geotechnical engineering of the bridge site included 3D laser scanning of the canyon walls, geologic mapping, core drilling,…
