Melnick, Joseph L. Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas.
Last reviewed:September 2019
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An acute, febrile, mosquito-borne viral disease. Yellow fever (see illustration) is a zoonotic disease transmitted by infected Aedes or Haemagogus mosquitoes, predominantly in tropical and subtropical areas of Africa and South America. In severe cases, yellow fever is characterized by jaundice, albuminuria (excessive leakage of the protein albumin into the urine), and hemorrhage. Inapparent infections also occur. Although yellow fever can be prevented by an effective vaccine, the disease has been difficult to control in certain regions of the world, leading to many epidemics in human populations. See also: Africa; Albumin; Asia; Epidemic; Hemorrhage; Infectious disease; Jaundice; Mosquito; Vaccination; Virus; Zoonoses
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