Comp, Philip C. Thrombosis and Coagulation Laboratory, Oklahoma Memorial Hospital, University of Oklahoma, Norman, Oklahoma.
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An enzyme that is a plasminogen activator. Urokinase cleaves the plasma protein plasminogen, forming the active enzyme plasmin, which subsequently degrades fibrin. Thus urokinase is an essential component in the fibrinolytic clot-dissolving system in the human body. Other plasminogen activators include tissue plasminogen activator and streptokinase. See also: Plasmin
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