Transgenic plant vaccines
Langridge, William H. R. Center for Molecular Biology and Gene Therapy, Loma Linda University, Loma Linda, California.
- Edible plants as mucosal vaccine production and delivery vehicles
- Medical and economic advantages of plant-based mucosal vaccines
- Types of plant-based vaccines
- Plant vaccine yield and dosage
- Plant vaccines can also suppress the development of autoimmune diseases
- Cost of production of plant-based vaccines
- Future plant vaccine applications
- Some concerns
- Links to Primary Literature
- Additional Readings
Edible vaccines generated in plants via genetic engineering. To increase the rate and accessibility of vaccination for the rapidly increasing world population, researchers have begun to explore the use of edible plants for the synthesis and delivery of oral vaccines against infectious and autoimmune diseases (Table 1). Application of modern techniques of molecular biology is contributing heavily toward the development of transgenic plant vaccines that offer protection against a growing number of human and animal diseases. When a plant-based vaccine has been consumed, the host initiates a mucosal immune response against the antigen synthesized in the plant and becomes immune to the pathogen from which the antigen was taken. See also: Genetic engineering; Genetically engineered plants; Vaccination
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