Rasmussen, Howard Department of Biochemistry, University of Pennsylvania, Philadelphia, Pennsylvania.
- Physiological activity
- Biochemical mechanisms
- Therapeutic value
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A hormone, the only known secretory product of the parenchymal or C cells of the mammalian thyroid and of the ultimobranchial glands of lower forms. The hormone has been isolated and characterized from porcine and human thyroid tissue as well as from fish ultimobranchial tissue. In all cases it is a polypeptide of 3800 molecular weight characterized by a single polypeptide chain. The amino acid sequence of the porcine hormone is The sequences of both the human and fish hormone have also been determined and are different from each other and from the porcine hormone except in the N-terminal seven amino acids. See also: Ultimobranchial bodies
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