DISCLAIMER: This article is being kept online for historical purposes. Though accurate at last review, it is no longer being updated. The page may contain broken links or outdated information.
Stress and depression
Mantella, Rose C. Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Lenze, Eric J. Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Reynolds, Charles F., III Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
- Hormonal involvement
- Stressful life events
- Sex differences in depression
- Recent findings and future directions
- Related Primary Literature
- Additional Reading
In 1992, G. P. Chrousos and P. W. Gold defined stress as a state of threatened homeostasis, or instability to which a person (or animal) reacts with an adaptive response to preserve its internal equilibrium. Mild, brief, and controllable challenges could be perceived as pleasant or exciting and could be a positive input for emotional and intellectual development. However, as defined by H. Selye in 1976, more intense, persistent, and uncontrollable situations of threat or perceived threat may lead to maladaptive responses. In humans, these maladaptive responses include the development of mood disorders.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 10,000 highly qualified scientists and 45 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information