St. John's wort: use as an antidepressant
Cott, Jerry M. Center for Drug Evaluation and Research, U.S. Food and Drug Administration, U.S. Department of Health and Human Services, Silver Spring, Maryland.
- Clinical effects in depression
- Use in pregnancy and nursing
- Animal toxicology studies
- Interaction with other medications
- Links to Primary Literature
- Additional Readings
St. John's wort [Hypericum perforatum L. (Hypericaceae)] is a perennial plant (see illustration) and one of the best-known and best-researched Western medicinal plants. It has been used for millennia as a result of its many medicinal properties; for example, St. John's wort has been used to aid wound healing and to treat kidney and lung ailments, insomnia, and depression. Although St. John's wort was at one time the most popular antidepressant in the German marketplace, concerns have arisen mainly because of reports of potential interactions with other drugs. It should also be noted that St. John's wort has not received any approval from the U.S. Food and Drug Administration (FDA) as a treatment for depression.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information