Stuart, Edward G. West Virginia School of Medicine, Morgantown, West Virginia.
Mottet, N. Karle University Hospital, University of Washington, Seattle, Washington.
Last reviewed:June 2020
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Pathologies of the spleen. The spleen is rarely the site of primary disorders except those of vascular origin, but it is frequently involved in systemic inflammations, metabolic diseases, and generalized blood disorders. Among vascular disturbances, acute and chronic congestion are prominent, particularly chronic congestion caused by cardiac failure, cirrhosis of the liver, and obstruction of the blood flow from the spleen by thrombi, scarring, or tumor tissue. Obstruction of the splenic artery or its branches by thrombi may result in an infarct caused by either cardiac or blood disease. See also: Spleen
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