Role of telomeres and centromeres in meiotic chromosome pairing
Tiang, Choon-Lin Department of Plant Breeding and Genetics, Cornell University, Ithaca, New York.
Pawlowski, Wojciech P. Department of Plant Breeding and Genetics, Cornell University, Ithaca, New York.
- Homologous chromosome pairing
- Telomere bouquet
- Telomere–nuclear envelope attachment and telo-mere dynamics
- Role of centromeres in chromosome pairing
- Links to Primary Literature
- Additional Readings
Meiosis is a process in which haploid cells are produced from diploid parent cells after two successive rounds of nuclear division. During the first division of meiosis, homologous chromosomes segregate to opposite poles of the dividing cell. Chromosome mis-segregation results in the eventual formation of aneuploid gametes, which may cause fertility problems and chromosomal abnormalities in the offspring, such as Down syndrome in humans.
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