Protein kinase D signaling
Rozengurt, Enrique Department of Medicine, University of California, Los Angeles, California.
- Model of PKD activation
- PKD function
- Links to Primary Literature
Hormones, neurotransmitters, and growth factors stimulate the production of intracellular messengers, including the lipid-derived diacylglycerol (DAG), in their target cells to modify their behavior. One of the prominent intracellular targets of DAG is the protein kinase C (PKC) family. However, the mechanisms by which PKC-mediated signals are decoded by the cell remain incompletely understood.
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