Ratnoff, Oscar D. Department of Medicine, Division of Hematology and Oncology, Case Western Research University, Cleveland, Ohio.
- Activation of plasminogen
- Physiologic actions of plasmin
- Links to Primary Literature
- Additional Readings
A proteolytic enzyme that can digest many proteins through the process of hydrolysis. Plasmin is found in plasma in the form of plasminogen, which is an inert precursor or zymogen; one site of synthesis is the liver. Plasma also contains inhibitors that limit either the transformation of plasminogen to plasmin (plasminogen activator inhibitors) or the action of plasmin (principally α2-antiplasmin and α2-macro-globulin).
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