Grundmann, Oliver Department of Medicinal Chemistry, University of Florida, Gainesville, Florida.
Last reviewed:June 2021
Show previous versions
- The preclinical drug development process
- Pharmaceutical chemistry as an interdisciplinary science
- Related Primary Literature
- Additional Reading
An interdisciplinary science focusing on aspects of the drug discovery process prior to testing the drug in humans, from early determination of a lead compound to structural optimization for drug delivery. Pharmaceutical chemistry informs many aspects of the preclinical drug discovery and development process to identify, synthesize, analyze, optimize, and test feasible drug candidates before they are administered to humans. The three requirements that all new drugs have to meet before they can be marketed are the following: (1) safety, (2) efficacy, and (3) purity. Through its interdisciplinary nature, pharmaceutical chemistry ensures all three requirements are thoroughly evaluated and tested.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 10,000 highly qualified scientists and 46 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information