Aloia, John F. Osteoporosis Diagnosis, Treatment, and Research Center, Department of Medicine, Winthrop-University Hospital, Mineola, New York.
Last reviewed:March 2018
Show previous versions
- Disease prevention
- Fracture prevention
- Diagnosis and treatment
- Links to Primary Literature
- Additional Readings
A metabolic bone disease in which the amount of bone tissue is reduced sufficiently to increase the likelihood of fracture. Osteoporosis involves deossification (the loss or removal of the mineral constituents of bone) with an absolute decrease in bone tissue (Fig. 1), including enlargement of marrow and Haversian spaces (which surround the nerves, blood vessels, and lymphatic structures of bone), decreased thickness of cortical bone (the dense, compact, outer surface of bone) and trabecular bone (the porous, inner layer of bone), and structural weakness. Individuals suffering from osteoporosis are subject to bone fractures. Fractures of the vertebrae, femur (thigh bone), and wrist are the most common osteoporotic fractures, but other bones, including the ribs, upper arm, and pelvis, may fracture as well. Although low bone mass is the major factor in osteoporotic fractures, there also may be qualitative and architectural changes in bone with aging that lead to increased fragility. See also: Aging; Bone; Bone disorders; Metabolic disorders
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8500 articles and Research Reviews covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information