Blumenthal, Thomas Molecular, Cellular, and Developmental Biology Department, University of Colorado, Boulder, Colorado.
Last reviewed:August 2020
- Regulation of operon expression
- Operons in eukaryotes
- Related Primary Literature
- Additional Reading
A group of distinct genes that are expressed and regulated as a unit. Each operon is a DNA sequence that is composed of a tightly linked cluster of genes. At the 5′ end of the gene cluster is a promoter, the site at which RNA polymerase binds to begin transcription. RNA polymerase moves down the operon, catalyzing the synthesis of an RNA molecule with a sequence complementary to DNA. Some operons contain additional promoters between genes in the operon. Only genes on the 3′ sides of these promoters are transcribed from these internal sites. See also: Deoxyribonucleic acid (DNA); Ribonucleic acid (RNA); Transcription
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