Cole, Michael Department of Molecular Biology, Princeton University, Princeton, New Jersey.
Last reviewed:February 2019
Show previous versions
- Genetic basis of neoplasia
- Mechanisms of oncogene formation
- Viral oncogenes
- Oncogene functions
- Oncogene-targeted cancer therapy
- Related Primary Literature
- Additional Reading
Any of the genes that contribute to the conversion of a normal cell into a cancerous cell. Oncogenes are defective genes that can cause a cell to divide in an unregulated manner, leading to cancer. Oncogenes can derive from cellular genes that undergo mutations that alter their expression or activity, or from viruses that carry oncogenes within their genome and are transferred into the cell by infection (Fig. 1). See also: Animal virus; Cancer; Cancer cell metabolism; Cell (biology); Cell division; Gene; Mutation; Oncology; Virus
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information