Groody, E. Patrick Integrated Genetics, Framingham, Massachusetts.
- Links to Primary Literature
- Additional Readings
A cellular constituent that is one of the building blocks of ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). In biological systems, nucleotides are linked by enzymes in order to make long, chainlike polynucleotides of defined sequence. The order or sequence of the nucleotide units along a polynucleotide chain plays an important role in the storage and transfer of genetic information. Many nucleotides also perform other important functions in biological systems. Some, such as adenosine triphosphate (ATP), serve as energy sources that are used to fuel important biological reactions. Others, such as nicotinamide adenine dinucleotide (NAD) and coenzyme A (CoA), are important cofactors that are needed to complete a variety of enzymatic reactions. Cyclic nucleotides such as cyclic adenosine monophosphate (cAMP) are often used to regulate complex metabolic systems. Chemically modified nucleotides such as fluoro-deoxyuridine monophosphate (Fl-dUMP) contain special chemical groups that are useful for inactivating the normal function of important enzymes. These and other such compounds are widely used as drugs and therapeutic agents to treat cancer and a variety of other serious illnesses. See also: Adenosine triphosphate (ATP); Coenzyme; Cyclic nucleotides; Nicotinamide adenine dinucleotide (NAD)
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8500 articles and Research Reviews covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information