Muscular system disorders
Sumi, S. Mark School of Medicine, University of Washington, Seattle, Washington.
Last reviewed:April 2019
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- Motor neuron damage
- Spinal muscular atrophies
- Amyotrophic lateral sclerosis
- Neuromuscular junction
- Genetic diseases
- Nongenetic or acquired diseases
- Metabolic diseases
- Related Primary Literature
- Additional Reading
Pathological conditions affecting skeletal (voluntary) muscles. The muscular system comprises the set of anatomical structures (muscle cells, contractile elements, and associated connective tissues) that are responsible for body movements in vertebrates. Pathological conditions or diseases of the muscular system can vary in their severity and longevity, and the origin of these disorders can involve congenital, acquired, or metabolic factors. Traumatic injuries are often involved as well. In addition, the proper functioning of other organ systems, such as the nervous system (Fig. 1) and endocrine system, and variations in the concentration of various electrolytes may affect muscle function. See also: Endocrine system (vertebrate); Muscle; Muscle proteins; Muscular system; Nervous system (vertebrate)
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