Gergely, John Department of Muscle Research, Boston Biomedical Research Institute, Boston, Massachusetts.
Last reviewed:April 2019
Show previous versions
- Activation by calcium
- Related Primary Literature
- Additional Reading
Specialized proteins in muscle cells that are the building blocks of the structures constituting the moving and regulatory machinery of muscles. The moving machinery of muscles comprises myofilaments that are discernible by electron microscopy. These myofilaments are of two kinds, that is, myosin and actin proteins, and their regular arrangement within muscle cells gives the striated pattern to skeletal muscle fibers (Fig. 1). It is recognized that the sliding of the two sets of filaments relative to each other is the molecular basis of muscle contraction. To understand the ultimate mechanism that causes the movement of these filaments relative to each other, it is necessary to consider the features of the individual molecules that make up these filaments. Practically all nonmuscle cells, although lacking the filaments of muscle, contain proteins similar to those found in muscle; these proteins are likely to be involved in cell motility and in determining properties of cell membranes. See also: Cell membranes; Muscle; Muscle development and regeneration; Muscular system; Protein
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information