Lunte, Craig E. Department of Chemistry, University of Kansas, Lawrence, Kansas.
- Probe design
- Related Primary Literature
- Additional Reading
An approach for sampling the extracellular space of essentially any tissue or fluid compartment in the body. Continuous sampling can be performed for long periods with minimal perturbation to the experimental animal. Microdialysis provides a route for sampling the extracellular fluid without removing fluid, and administering compounds without adding fluid. The resulting sample is clean and amenable to direct analysis. Microdialysis was initially developed to study neurochemical processes in the brain. The success of this technique in the study of neurotransmitter release has led to the development of microdialysis techniques for general pharmacokinetic and drug distribution studies.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 10,000 highly qualified scientists and 45 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information