Schauer, Nicolas De Ruiter Seeds, Bergschenhoek, The Netherlands.
Last reviewed:August 2020
Show previous versions
- Metabolomic analyses and techniques
- Applications of metabolite profiling
- Research opportunities
- Related Primary Literature
- Additional Reading
The general term for the study of the global metabolite composition of a biological system—the metabolome—under a given set of conditions. Metabolomics is the scientific investigation of small-molecule metabolic products, collectively termed the metabolome, found within biological systems (for example, cells, tissues, biological fluids, and organs). In particular, metabolomics can help researchers to delineate the phenotypes (characteristics) and responses of the small molecules (low-molecular-weight organic compounds, such as sugars, amino acids, nucleotides, and lipids) associated with biological metabolism (Fig. 1). The investigation of the metabolome of a biological system can be defined by a range of terms: metabolite profiling, metabolite fingerprinting, metabonomics, and metabolomics. In general, metabolite profiling is used to describe the rapid, but accurate quantification and identification of metabolites using a single analytical technique. Mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy are the two most commonly used techniques. Overall, metabolite profiling is utilized in numerous research areas. Its application includes diagnostics, analysis of cell function, identification of gene function, recognition of disease biomarkers, precision medicine, discovery of novel biochemical and biotechnology targets for therapeutic purposes, and systems biology. See also: Biotechnology; Cell (biology); Mass spectrometry; Metabolic networks; Metabolism; Nuclear magnetic resonance (NMR); Plant metabolism
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 10,000 highly qualified scientists and 45 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information