Walkley, Steven U. Department of Neuroscience, Rose F. Kennedy Children’s Evaluation and Rehabilitation Center, Albert Einstein College of Medicine, Bronx, New York.
Holtzman, Eric Department of Biological Sciences, Columbia University, New York, New York.
- Principal roles
- Involvement in disease
- Plants, yeast, and fungi
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A membrane-bounded digestive structure found within virtually all types of animal cells. Lysosome sizes, microscopic appearances, and other properties vary among different cell types and circumstances, owing in part to differences in their functions and states. Typical lysosomes (Figs. 1 and 2) are roughly spherical or elongate bodies, with largest dimensions of 0.1–1 μm (0.000004–0.00004 in.) or greater. Tens to hundreds may be present in a single cell. See also: Cell (biology); Cell organization
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