Burgdorfer, Willy Rocky Mountain Laboratories, Department of Health and Human Services, National Institutes of Health, Hamilton, Montana.
Kazmierczak, James J. Bureau of Public Health, Madison, Wisconsin.
Last reviewed:June 2019
Show previous versions
- Lyme disease in humans
- Causative agent
- Diagnosis and treatment
- Prevention and control
- Lyme disease in animals
- Related Primary Literature
- Additional Reading
A complex multisystem illness caused by the tick-borne spirochetal bacterium, Borrelia burgdorferi. Lyme disease, also known as Lyme borreliosis, is an infectious disease of growing concern. Without early and proper treatment, individuals who have been infected with Borrelia burgdorferi can develop a number of debilitating symptoms, including severe joint pain, fatigue, headaches, and problems involving the central nervous system. It generally begins with a unique expanding skin lesion at the site of a tick bite (Fig. 1). This skin lesion, referred to as erythema migrans, is often accompanied by symptoms resembling those of influenza or meningitis. During the weeks or months following the tick bite, some individuals may develop cardiac and neurological abnormalities, particularly meningitis or inflammation of the cranial or peripheral nerves. If the disease is untreated, intermittent or chronic arthritis and progressive encephalomyelitis may develop months or years after the primary infection. See also: Bacteria; Borrelia; Central nervous system; Infectious disease; Medical bacteriology; Nervous system disorders; Skin; Zoonoses
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 10,000 highly qualified scientists and 46 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information