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Imaging of developmental biological processes
Bailey, Caleb M. Stowers Microscopy Center, Stowers Institute for Medical Research, Kansas City, Missouri.
Kulesa, Paul M. Imaging Center, Stowers Microscopy Center, Stowers Institute for Medical Research, Kansas City, Missouri.
- Fluorescence-based imaging
- Imaging innovations and strategies
- Integration of gene expression analysis
- Future outlook
- Related Primary Literature
- Additional Reading
Organismal development typically begins with a single cell and finishes with a highly organized three-dimensional structure. Through coordinated cell division, guided cell migration, cell segregation, and differentiation, cells are organized into distinct tissues. These tissues then create complex, integrated organ systems that function in a cooperative manner to promote life. Microscopy has proven an indispensable tool to visualize and analyze individual cell and tissue behaviors within the living embryo, thus elucidating complex developmental biological processes.
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