Hepatitis C virus
Selzner, Nazia Multi-Organ Transplant Program, University Health Network, Toronto, Ontario, Canada.
Khattar, Ramzi Multi-Organ Transplant Program, University Health Network, Toronto, Ontario, Canada.
Levy, Gary A. Multi-Organ Transplant Program, University Health Network, and Department of Laboratory Medicine and Pathobiology, Toronto General Hospital, Toronto, Ontario, Canada.
- Natural history
- Future directions
- Links to Primary Literature
- Additional Readings
Hepatitis C virus (HCV) remains a leading cause of chronic liver disease worldwide, with an estimated 150 million individuals, or 3% of the world's population, chronically infected. Furthermore, HCV is the leading indication for liver transplantation and has surpassed HIV as a leading cause of death. Since 2000, there has been an increase of 92% in the incidence of cirrhosis of the liver, resulting in a 126% increase in the incidence of liver failures and a 102% increase in the incidence of hepatocellular carcinoma (HCC), all attributed to HCV, placing an increasing burden on health-care systems.
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