DISCLAIMER: This article is being kept online for historical purposes. Though accurate at last review, it is no longer being updated. The page may contain broken links or outdated information.
Barrow, Jeffery R. Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah.
- Early work
- Contributions of gene targeting to modern medicine
- Future of gene targeting
- Related Primary Literature
- Additional Reading
It has been recognized for some time that the humble house mouse is an extremely valuable research tool for human medicine. Despite the outward differences in appearance, mice and humans are actually quite closely related with respect to general body plan and physiology, and at the genetic level. Mice and humans share approximately 99% of their genes. That is, if one takes any human gene, there is 99% likelihood that there will be a mouse correlate. Given the high degree of genetic conservation between mice and humans, as well as many ideal laboratory characteristics (such as inexpensive husbandry and rapid life cycle) of mice, it is not surprising that the mouse has come to the forefront of modern medical science as a model for understanding the individual functions of human genes and the genetic disorders that afflict humans.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 10,000 highly qualified scientists and 46 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information