Ramage, Gordon School of Medicine, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Williams, Craig Department of Microbiology, Royal Hospital for Sick Children, Glasgow, United Kingdom.
- Clinical significance
- Developmental characteristics
- Pathogenesis of fungal biofilms
- Links to Primary Literature
- Additional Readings
Microbiologists have historically studied homogeneous planktonic (that is, free-floating) cells in pure culture. However, the link between heterogeneous sessile (that is, surface-attached) cells, microbial pathogenesis, and human infection is now widely accepted. It is apparent that a wide range of bacteria and fungi are able to alternate between planktonic growth and sessile multicellular communities, commonly referred to as biofilms. In fact, up to 80% of all microorganisms in the environment exist in biofilm communities.
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