Mannheim, Walter Med. Zentrum für Hygiene, Universität Marburg, Marburg, Germany.
Last reviewed:February 2020
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A genus of very small, coccoid to ellipsoidal, pleomorphic, nonmotile and nonsporulating, Gram-negative, rod-shaped bacteria. The Francisella bacterium was named for Edward Francis, who studied the organism that causes tularemia. Fastidious and strictly aerobic, it grows at 37°C (98.6°F) within several days, but only in enriched media, such as coagulated egg yolk or glucose-cysteine-blood-agar. The genus is catalase-negative. Acid is produced from several carbohydrates; indole, urease, gelatinase, and nitrate reductase are not formed. The genome deoxyribonucleic acid (DNA) contains 32–36 mol % guanine plus cytosine. The organisms occur in natural waters of the Northern Hemisphere, and can be parasitic and pathogenic in birds, anthropods, and mammals, including humans. See also: Bacteria; Bacteriology; Medical bacteriology; Medical parasitology; Tularemia
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