Rae, Peter M. M. Molecular Diagnostics, Inc., West Haven, Connecticut.
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In split genes, a portion that is included in the ribonucleic acid (RNA) transcript of a gene and survives processing of the RNA in the cell nucleus to become part of a spliced messenger RNA (mRNA) or structural RNA in the cell cytoplasm. Split genes are those in which regions that are represented in mature mRNAs or structural RNAs (exons) are separated by regions that are transcribed along with exons in the primary RNA products of genes, but are removed from within the primary RNA molecule during RNA processing steps (introns) [see illustration]. See also: Gene; Intron; Ribonucleic acid (RNA)
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