Fanta, Paul E. Department of Chemistry, Illinois Institute of Technology, Chicago, Illinois.
- Diene component
- Dienophile component
- Reaction conditions
- Related Primary Literature
- Additional Reading
The 1,4-addition of an alkene (the dienophile) to a conjugated diene. The reaction, also known as the diene synthesis, is one of the most valuable and versatile methods for the preparation of compounds containing a six-membered ring, and proceeds most rapidly when the dienophile is substituted by electron-attracting groups, such as CO or CN [reactions (1) and (2)].
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