DISCLAIMER: This article is being kept online for historical purposes. Though accurate at last review, it is no longer being updated. The page may contain broken links or outdated information.
Romero, Jan Antoinette C. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.
Molander, Gary A. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.
- Modes of activation
- Reactions of alkenes
- Reactions of alkynes
- Intramolecular hydroamination reactions
- Related Primary Literature
- Additional Reading
Nitrogen-containing compounds are widespread in nature, are pharmacologically interesting compounds, and are used in the synthesis of fine chemicals. Because of their pervasiveness in the chemical industry, the selective generation of amines remains of fundamental importance to the synthetic organic chemist. Among the standard methods for their synthesis, N-alkylation of ammonia, reductive amination of aldehydes or ketones, reduction of amides, and aminations of olefins using stoichiometric promoters are the most common. Although these routes are well developed, they are often not implemented when large amounts of amines are needed. These reactions suffer from the production of vast amounts of by-products created during the process, the elimination of which is costly and environmentally unfriendly.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 10,000 highly qualified scientists and 45 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information