Calderone, Richard Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC.
- Types of candidiasis
- Pathogenesis of invasive candidiasis
- Diagnosis of candidemia and invasive candidiasis
- Links to Primary Literature
- Additional Readings
A genus comprising yeastlike fungi that cause a variety of human diseases referred to as candidiasis. All Candida species are single-celled yeasts that are ovoid in shape and 3–5 μm in size, and they multiply by a process called budding. Most of these species also produce filamentous growths, which appear as segmented tubelike structures (usually called pseudohyphae) that emerge as outgrowths from the unicellular yeasts. The most common species of the genus Candida that cause disease are C. albicans, C. glabrata, C. parapsilosis, C. tropicalis, and C. krusei. In particular, the frequency of disease caused by the last four species has increased since the introduction of fluconazole, an antifungal agent, because they are more often fluconazole-resistant. See also: Drug resistance; Fungal infections; Fungi; Fungistat and fungicide; Medical mycology; Yeast
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