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Bronchiolitis obliterans organizing pneumonia (BOOP)
Article By:
Pierce, Marcia M. Department of Biological Sciences, Eastern Kentucky University, Richmond, Kentucky.
Last reviewed:2008
DOI:https://doi.org/10.1036/1097-8542.YB081110
Bronchiolitis obliterans organizing pneumonia was first described in 1985 by Gary Epler as a disease distinct from other disorders of the lungs; it is also known as Epler's pneumonia. It is characterized by the formation of connective tissue masses in the lungs, filling the respiratory bronchioles and making breathing difficult and painful. BOOP presents clinically with initial “flulike” symptoms, followed by progressive dyspnea (shortness of breath), cough, fever, and weight loss. “Crackling” can be heard within the chest using a stethoscope. X-ray imagery shows bilateral patchy infiltrates in the alveoli of the lungs. Computed tomography (CT) shows bilateral areas of lung consolidation. This appears with a “ground-glass” haziness that is characteristic for the disease.
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