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Broadly neutralizing antibodies
Torres, Raul M. Integrated Department of Immunology, University of Colorado School of Medicine and National Jewish Health, Denver, Colorado.
Pujanauski, Lindsey Integrated Department of Immunology, University of Colorado School of Medicine and National Jewish Health, Denver, Colorado.
- HIV broadly neutralizing antibodies
- Influenza broadly neutralizing antibodies
- New strategies for inducing viral broadly neutralizing antibodies
- Related Primary Literature
- Additional Reading
Broadly neutralizing antibodies are immune proteins that inhibit or abolish the biological activity of a wide range of antigenically diverse viruses. Recently, broadly neutralizing antibodies have been identified for human immunodeficiency virus (HIV) and influenza virus infections, and these antibodies are capable of neutralizing many or all viral variants. The antigenic determinants (epitopes) identified by these antibodies are therefore exciting targets for vaccine design if certain biological problems can be surmounted.
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