Chenault, H. Keith E. I. DuPont de Nemours, Central Research & Development, Wilmington, Delaware.
Last reviewed:August 2019
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- Natural product synthesis
- Protein structure, design, and mimicry
- Protein folding
- Protein mimicry
- Expanding the repertoire of genetically coded amino acids
- Enzymatic catalysis
- Mechanisms of rate increase
- Catalytic antibodies
- Selectivity of enzymatic catalysis
- Enzyme mimics
- Enzymes in organic synthesis
- Metabolic engineering
- Nucleic acids
- Mechanisms of drug action
- Related Primary Literature
- Additional Reading
The science that describes the structure, reactivity, and interactions of organic compounds of biological significance. It represents the meeting of biochemistry, in its broadest sense, with organic chemistry in an attempt to describe and control complex biological systems at the molecular level. Areas of research include enzymatic catalysis, the structure and folding of proteins, the structure and function of biological membranes, the chemistry of poly(ribonucleic acid) [RNA] and poly(deoxyribonucleic acid) [DNA], metabolic pathways, diseases, immunology, and mechanisms of drug action. Bioorganic chemistry seeks not only to understand and control cellular and biochemical processes, but also to mimic them. See also: Biochemistry; Organic chemistry
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