Hart, Ronald W. Department of Health and Human Services, National Center for Toxicological Research, Jefferson, Arizona.
Turturro, Angelo National Center for Toxicological Research, Department of Health and Human Services, Jefferson, Arkansas.
Last reviewed:February 2019
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A method for quantitatively determining the concentration, biological activity, or potency of a substance by its effect on the growth of a suitable animal, plant, or microorganism under controlled conditions. A bioassay (biological assay) is a measurement procedure that quantifies the effect of a living system's exposure to a substance. It also can quantitate the concentration or potency of a substance by some observable effect on a biological system. For example, bioassays can determine precisely how much a delivered substance affects the growth of an organism (animal, plant, or microorganism) under regulated conditions (see illustration), or the relative potency of a drug, enzyme, or hormone preparation on cells. See also: Biotechnology; Enzyme; Experiment; Hormone
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