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Bicarbonate physiology and pathophysiology
Boron, Walter F. Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Parker, Mark D. Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
- Maintenance of blood plasma pH
- Maintenance of pH in and around cells
- Support of HCO3− secretion
- Support of gas exchange in red blood cells
- Related Primary Literature
- Additional Reading
Bicarbonate (HCO3−) is a small inorganic negative ion (anion) that is familiar as a constituent of baking soda (sodium bicarbonate; NaHCO3). Baking soda is a leavening agent: in dough, HCO3− dissolved in water reacts with acids (H+) to form carbon dioxide [CO2; see Eq. (1)].
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