McManus, David D. Cardiac Electrophysiology Section, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
Magnani, Jared W. Section of Cardiovascular Medicine, Department of Medicine, Boston University, Boston, Massachusetts.
Rienstra, Michiel Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Benjamin, Emelia J. Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, Massachusetts.
Last reviewed:March 2020
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- Advances in pathogenesis
- Genetic basis
- Atrial remodeling and noninvasive markers of electrical remodeling
- Novel biomarkers
- Advances in treatment
- Upstream therapies
- Rate control
- Novel anticoagulants
- Novel antiarrhythmic medications
- Related Primary Literature
- Additional Reading
The most common type of arrhythmia (any disorder of the heart rate or rhythm). Atrial fibrillation, often abbreviated AFib or AF, is a heart condition that can lead to potentially serious complications. It is associated with decreased quality of life and increased risk of cognitive decline, dementia, stroke, heart failure (HF), and mortality. The adverse public health impact of atrial fibrillation is increasing around the world (Fig. 1), and the associated annual health-care costs are estimated to be in the tens of billions of dollars. See also: Cardiovascular system; Heart (vertebrate); Heart disorders
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