Sinha, Shweta Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
- Artemisinin and its derivatives
- Mode of action
- Artemisinin resistance
- Related Primary Literature
- Additional Reading
A sesquiterpene lactone (C15H22O5), derived from the leaves of Artemisia annua (sweet wormwood or qinghao), which is known for its antimalarial activity. Artemisinin (C15H22O5; see illustration) is an important antimalarial agent. Around 2000 years ago, artemisinin was used as an herbal remedy by Chinese herbal medicine practitioners. The discovery of artemisinin in the early 1970s as a therapy for malaria was a remarkable medical achievement. Chinese pharmaceutical chemist Youyou Tu was awarded the 2015 Nobel Prize in Physiology or Medicine for discovering artemisinin as a most efficacious and safe antimalarial drug. Presently, artemisinin-based combination therapies (ACTs) are recommended by the World Health Organization (WHO) as the first-line treatment for malaria caused by the parasite Plasmodium falciparum. See also: Malaria; Medical parasitology; Medicine; Parasitology; Pharmaceutical chemistry; Pharmacology; Pharmacy
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information