Ryoo, Hyung Don Department of Cell Biology, New York University School of Medicine, New York, New York.
Last reviewed:January 2019
Show previous versions
- Cell death
- Role in animal development and disease
- Molecular regulators of apoptosis
- Exploiting apoptosis for treatment of cancer
- Related Primary Literature
- Additional Reading
Programmed cell death triggered by extracellular signals or genetically determined events and carried out by physiological processes within the cell. Apoptosis is one of the major forms of cell death in multicellular organisms (necrosis is the other form). Also referred to as programmed cell death, apoptosis is defined by specific changes in cell morphology, followed by the engulfment of the cell corpse by phagocytes (Fig. 1). Often, the death of certain cells through apoptosis enhances the overall health of an individual. The term apoptosis originates from a Greek word that means "to fall," as happens to the foliage of tree leaves in autumn, which helps the tree's survival. Defects in apoptosis are associated with a large number of diseases in humans. The most notable of these diseases are cancers. See also: Cancer; Cell (biology); Death; Oncology
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information