Pierce, Marcia M. Department of Biological Sciences, Eastern Kentucky University, Richmond, Kentucky.
Last reviewed:January 2019
Show previous versions
- Rise of antibiotic resistance in bacteria, published June 2016:Download PDF Get Adobe Acrobat Reader
- Identification of antibiotics
- First development of resistance
- Modern issues
- Clostridium difficile
- Gram-negative superbugs
- Resistance mechanisms
- Links to Primary Literature
- Additional Readings
The capability that a bacterium acquires to counteract an inhibitory chemical molecule or compound that was formerly effective in killing it or preventing its growth. Antibiotic resistance in bacteria (Fig. 1) is a hot topic in the media and in scientific and health care settings worldwide. The U.S. Centers for Disease Control and Prevention (CDC) describes antibiotic-resistant bacteria as “nightmare bacteria” that pose a catastrophic threat to people in every country in the world. It is estimated that 2 million people in the United States become infected by resistant bacteria each year. The CDC indicates that at least 23,000 people die per year as a direct result of antibiotic-resistant infections, with more individuals dying because of complications that occur as a result of these infections. The CDC classifies three types of infections as urgent threats to public health: (1) carbapenem-resistant Enterobacteriaceae (CRE); (2) drug-resistant gonorrhea; and (3) Clostridium difficile, which is linked to serious diarrheal illnesses associated with antibiotic use. The current status of antibiotic resistance worldwide needs to be investigated meticulously, and ways must be found to halt its progression. See also: Antibiotic; Antimicrobial agents; Antimicrobial resistance; Bacteria; Bacteriology; Drug resistance; Infection; Medical bacteriology; Microbiology; Public health
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8700 articles covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information