Delefosse, Thomas Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois.
Yoder, Anne D Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois.
- Research challenges
- Research techniques
- Ancient human DNA
- Links to Primary Literature
- Additional Readings
Within the past decade, biochemical methods have advanced so much that deoxyribonucleic acid (DNA) can be copied and sequenced from individuals representing extinct populations, or even from individuals representing entire species now extinct. Such DNA, from long-gone sources, is called ancient DNA (aDNA). The introduction of the polymerase chain reaction (PCR) into the molecular biologist's tool box has made this extraordinary retrieval possible. The PCR is a biochemical technique in which free nucleotides, DNA primer sequences, and a polymerase (Taq) are employed to amplify DNA in vitro. Theoretically, it is possible to begin with a single target DNA molecule and end with millions of copies that can easily be sequenced with routine methods.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Contributors include more than 9000 highly qualified scientists and 43 Nobel Prize winners.
MORE THAN 8500 articles and Research Reviews covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 19,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information