Acquired immunological tolerance
Sykes, Megan Transplantation Biology Research Center, Massachusetts General Hospital, Charlestown, Massachusetts.
Last reviewed:October 2019
- Autoimmune disease
- Organ transplantation
- Central tolerance
- Peripheral tolerance
- Related Primary Literature
- Additional Reading
An induced state in which antigens originally regarded as foreign become regarded as self by the immune system. Tolerance can be induced (tolerization) in all of the cells of the immune system, including T cells (also known as T lymphocytes), the antibody-forming B cells (also known as B lymphocytes), and natural killer cells. Artificially induced immunological tolerance can be helpful in a number of clinical settings.
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