Atomic force microscopy
Dufrêne, Yves F. Université catholique de Louvain, Louvain-la-Neuve, Belgium.
Last reviewed:October 2019
- Principle and technique
- Operational modes
- Nanoscale visualization of biological structures
- Detecting and manipulating single biomolecules
- Measuring molecular recognition forces
- Related Primary Literature
- Additional Reading
A form of microscopy in which a sharp tip is scanned over the surface of a sample while sensing the interaction force between the tip and the sample. Due to its ability to observe and manipulate surfaces in aqueous solution, atomic force microscopy (AFM) has revolutionized the way in which microscopists explore biological structures, from single molecules to living cells.
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