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A macromolecule derived from natural sources; also known as biological polymer. Nature has developed effective means for efficiently preparing and...
One traditional approach to categorizing polymers is by their origin. Polymers can be roughly divided into synthetic polymers and naturally occurring...



= Encyclopedia Article; = Research Update
Figure 1.Two examples of PEGylation of proteins via an azide-functional nonnatural amino acid.
Figure 2.All-synthetic method for the preparation of the PEGylated protein SEP. Four different polypeptide modules are synthesized and coupled via ligation (steps 3, 5, and 8). The PEG chains are introduced via a process called oximation (steps 1 and 2). (Reprinted with permission from G. G. Kochendoerfer et al., Science, 299(5608):884–887, 2003. Copyright 2003 AAAS)
Figure 3.Three levels of polymer drug delivery. (a) A polymer is used as carrier of drugs, (b) The drugs are connected to the polymer via cleavable peptide linkers. (c) A homing device is added to target specific tissue types.