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Search Results: Microfabrication (nerve repair)

If their axons are severed, nerves in the peripheral nervous system retract from the injury site and sprout growth cones from the tips of the...


= Encyclopedia Article; = Research Update
Figure 1.Mechanism for growth cone guidance. With operative alignment, the axon must be physically aligned with the target. For neurotropism, the growth cone follows a chemotactic gradient of neurotransmitters secreted by the target tissue. With contact guidance, the axons follow physical guideposts to reach their target. In neurotrophism, growth cones will reach a target and receive chemical support if it is the correct one.
Figure 2.Micropatterned polymer substrate with microgrooves that are 10 µm wide and 3.4 µm deep with 10 µm spacing between grooves.
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